Trait
Patchy baldness
Clinical name: Patchy alopecia
Transient, non-scarring hair loss and preservation of the hair follicle located in in well-defined patches.
Summary
- Also called
- Alopecia areata
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
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Get my Genome Test28 genes linked to Patchy baldness
Changes in these genes cause rare conditions in which Patchy baldness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| COL17A1collagen type XVII alpha 1 chain | Always | In 1 condition |
| IL2RAinterleukin 2 receptor subunit alpha | Always | In 1 condition |
| LAMB3laminin subunit beta 3 | Always | In 1 condition |
| TRA2Btransformer 2 beta homolog | Always | In 1 condition |
| DSG4desmoglein 4 | Very often (80–99%) | In 1 condition |
| EBPEBP cholestenol delta-isomerase | Very often (80–99%) | In 2 conditions |
| HRHR lysine demethylase and nuclear receptor corepressor | Very often (80–99%) | In 1 condition |
| KDM5Clysine demethylase 5C | Very often (80–99%) | In 2 conditions |
| KRT81keratin 81 | Very often (80–99%) | In 1 condition |
| KRT83keratin 83 | Very often (80–99%) | In 1 condition |
| KRT86keratin 86 | Very often (80–99%) | In 1 condition |
| EXOSC2exosome component 2 | Often (30–79%) | In 1 condition |
| LMNAlamin A/C | Often (30–79%) | In 1 condition |
| PORCNporcupine O-acyltransferase | Often (30–79%) | In 2 conditions |
| TRACT cell receptor alpha constant | Often (30–79%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Often (30–79%) | In 1 condition |
| AIREautoimmune regulator | Sometimes (5–29%) | In 1 condition |
| ASLargininosuccinate lyase | Sometimes (5–29%) | In 1 condition |
| BLMBLM RecQ like helicase | Sometimes (5–29%) | In 1 condition |
| KCTD1potassium channel tetramerization domain containing 1 | Sometimes (5–29%) | In 1 condition |
| PADI3peptidyl arginine deiminase 3 | Sometimes (5–29%) | In 1 condition |
| SEL1LSEL1L adaptor subunit of SYVN1 ubiquitin ligase | Sometimes (5–29%) | In 1 condition |
| TGM3transglutaminase 3 | Sometimes (5–29%) | In 1 condition |
| HRASHRas proto-oncogene, GTPase | Rarely (1–4%) | In 1 condition |
| ADAM17ADAM metallopeptidase domain 17 | Not recorded | In 1 condition |
| ECM1extracellular matrix protein 1 | Not recorded | In 1 condition |
| NECTIN4nectin cell adhesion molecule 4 | Not recorded | In 1 condition |
| TP63tumor protein p63 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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