Trait
Congenital contracture
One or more flexion contractures (a bent joint that cannot be straightened actively or passively) that are present at birth.
Summary
- Also called
- congenital contractures, Congenital joint contractures
- Body system
- Abnormality of the musculoskeletal system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Congenital contracture, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test32 genes linked to Congenital contracture
Changes in these genes cause rare conditions in which Congenital contracture is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GFM2GTP dependent ribosome recycling factor mitochondrial 2 | Always | In 1 condition |
| MUSKmuscle associated receptor tyrosine kinase | Always | In 1 condition |
| ZBTB42zinc finger and BTB domain containing 42 | Always | In 1 condition |
| CHST14carbohydrate sulfotransferase 14 | Very often (80–99%) | In 1 condition |
| DSEdermatan sulfate epimerase | Very often (80–99%) | In 1 condition |
| FBN2fibrillin 2 | Very often (80–99%) | In 1 condition |
| ALG14ALG14 UDP-N-acetylglucosaminyltransferase subunit | Often (30–79%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Often (30–79%) | In 1 condition |
| CACNA1Ecalcium voltage-gated channel subunit alpha1 E | Often (30–79%) | In 1 condition |
| RYR3ryanodine receptor 3 | Often (30–79%) | In 1 condition |
| STAC3SH3 and cysteine rich domain 3 | Often (30–79%) | In 1 condition |
| TSEN54tRNA splicing endonuclease subunit 54 | Often (30–79%) | In 1 condition |
| AUTS2activator of transcription and developmental regulator AUTS2 | Sometimes (5–29%) | In 1 condition |
| COL12A1collagen type XII alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| KIF26Akinesin family member 26A | Sometimes (5–29%) | In 1 condition |
| LMOD3leiomodin 3 | Sometimes (5–29%) | In 1 condition |
| PAX7paired box 7 | Sometimes (5–29%) | In 1 condition |
| TBX4T-box transcription factor 4 | Sometimes (5–29%) | In 1 condition |
| ADGRG6adhesion G protein-coupled receptor G6 | Not recorded | In 1 condition |
| DNM2dynamin 2 | Not recorded | In 1 condition |
| DPM2dolichyl-phosphate mannosyltransferase subunit 2, regulatory | Not recorded | In 1 condition |
| ERGIC1endoplasmic reticulum-golgi intermediate compartment 1 | Not recorded | In 1 condition |
| FKRPfukutin related protein | Not recorded | In 1 condition |
| FKTNfukutin | Not recorded | In 1 condition |
| LARGE1LARGE xylosyl- and glucuronyltransferase 1 | Not recorded | In 1 condition |
| MYH2myosin heavy chain 2 | Not recorded | In 1 condition |
| NALCNsodium leak channel, non-selective | Not recorded | In 1 condition |
| NEBnebulin | Not recorded | In 1 condition |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Not recorded | In 1 condition |
| POMT1protein O-mannosyltransferase 1 | Not recorded | In 1 condition |
| POMT2protein O-mannosyltransferase 2 | Not recorded | In 2 conditions |
| VRK1VRK serine/threonine kinase 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks