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Gene

RYR3

ryanodine receptor 3

Summary

Cytogenetic location
15q13.3-q14
Coordinates
Chromosome 15: 33,310,967–33,866,102 (GRCh38)
Exons
104 exons across 555.1 kb
Protein
4,870 amino acids
MANE Select transcript
ENST00000634891.2NM_001036.6
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads RYR3 yet. The test sequences your whole genome, so your data includes it all the same.

How RYR3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 15, with a bracket where RYR3 sits. RYR3 and 12 genes near it on chromosome 15, from 32,755,831 to 34,421,238.Chromosome 1515q13.3-q14p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q14q15.1q15.2q15.3q21.1q21.2q21.3q22.1q22.2q22.31q22.32q22.33q23q24.1q24.2q24.3q25.1q25.2q25.3q26.1q26.2q26.332.8 Mb33 Mb33.2 Mb33.4 Mb33.6 Mb33.8 Mb34 Mb34.2 Mb34.4 MbFMN1: 32,765,544–33,194,727, reverse strandFMN1RYR3: 33,310,967–33,866,102, forward strandRYR3AVEN: 33,836,372–34,075,155, reverse strandAVENCHRM5: 33,968,260–34,067,458, forward strandCHRM5EMC7: 34,075,970–34,101,929, reverse strandEMC7PGBD4: 34,102,083–34,108,686, forward strandPGBD4KATNBL1: 34,140,365–34,210,119, reverse strandKATNBL1EMC4: 34,224,997–34,230,161, forward strandEMC4SLC12A6: 34,229,784–34,338,060, reverse strandSLC12A6NOP10: 34,339,159–34,343,180, reverse strandNOP10NUTM1: 34,343,315–34,357,737, forward strandNUTM1LPCAT4: 34,358,633–34,367,706, reverse strandLPCAT4GOLGA8A: 34,378,935–34,437,851, reverse strandDiagram of RYR3: 104 exons on the forward strand of chromosome 15Exon 40: 2 known disease-causing sitesExon 1: 33,310,967–33,311,096, 130 basesExon 2: 33,473,419–33,473,538, 120 basesExon 3: 33,503,631–33,503,738, 108 basesExon 4: 33,530,592–33,530,666, 75 basesExon 5: 33,533,311–33,533,389, 79 basesExon 6: 33,539,350–33,539,462, 113 basesExon 7: 33,540,791–33,540,890, 100 basesExon 8: 33,543,622–33,543,715, 94 basesExon 9: 33,548,130–33,548,204, 75 basesExon 10: 33,550,160–33,550,316, 157 basesExon 11: 33,562,837–33,563,010, 174 basesExon 12: 33,566,678–33,566,799, 122 basesExon 13: 33,579,976–33,580,144, 169 basesExon 14: 33,581,508–33,581,643, 136 basesExon 15: 33,584,395–33,584,490, 96 basesExon 16: 33,585,998–33,586,116, 119 basesExon 17: 33,601,419–33,601,552, 134 basesExon 18: 33,603,123–33,603,364, 242 basesExon 19: 33,613,183–33,613,375, 193 basesExon 20: 33,623,807–33,624,023, 217 basesExon 21: 33,628,471–33,628,575, 105 basesExon 22: 33,629,940–33,630,043, 104 basesExon 23: 33,631,210–33,631,293, 84 basesExon 24: 33,632,949–33,633,108, 160 basesExon 25: 33,634,586–33,634,733, 148 basesExon 26: 33,635,614–33,635,819, 206 basesExon 27: 33,636,376–33,636,550, 175 basesExon 28: 33,644,311–33,644,519, 209 basesExon 29: 33,646,351–33,646,526, 176 basesExon 30: 33,647,424–33,647,460, 37 basesExon 31: 33,649,072–33,649,235, 164 basesExon 32: 33,652,718–33,652,883, 166 basesExon 33: 33,659,720–33,659,806, 87 basesExon 34: 33,660,197–33,660,423, 227 basesExon 35: 33,662,153–33,662,948, 796 basesExon 36: 33,663,537–33,663,737, 201 basesExon 37: 33,669,354–33,669,456, 103 basesExon 38: 33,670,419–33,670,556, 138 basesExon 39: 33,696,218–33,696,491, 274 basesExon 40: 33,697,882–33,697,996, 115 basesExon 41: 33,699,704–33,699,833, 130 basesExon 42: 33,700,977–33,701,080, 104 basesExon 43: 33,706,919–33,707,054, 136 basesExon 44: 33,722,715–33,722,895, 181 basesExon 45: 33,724,065–33,724,176, 112 basesExon 46: 33,726,386–33,726,506, 121 basesExon 47: 33,728,857–33,729,026, 170 basesExon 48: 33,731,474–33,731,694, 221 basesExon 49: 33,736,235–33,736,325, 91 basesExon 50: 33,738,450–33,738,590, 141 basesExon 51: 33,739,832–33,739,995, 164 basesExon 52: 33,742,366–33,742,444, 79 basesExon 53: 33,746,068–33,746,157, 90 basesExon 54: 33,748,114–33,748,260, 147 basesExon 55: 33,748,468–33,748,530, 63 basesExon 56: 33,749,979–33,750,054, 76 basesExon 57: 33,750,163–33,750,286, 124 basesExon 58: 33,755,065–33,755,180, 116 basesExon 59: 33,756,306–33,756,373, 68 basesExon 60: 33,757,475–33,757,596, 122 basesExon 61: 33,768,658–33,768,707, 50 basesExon 62: 33,769,112–33,769,172, 61 basesExon 63: 33,771,920–33,772,158, 239 basesExon 64: 33,773,534–33,773,615, 82 basesExon 65: 33,780,211–33,780,341, 131 basesExon 66: 33,785,662–33,785,982, 321 basesExon 67: 33,788,218–33,788,458, 241 basesExon 68: 33,800,770–33,800,857, 88 basesExon 69: 33,801,869–33,801,961, 93 basesExon 70: 33,807,555–33,807,569, 15 basesExon 71: 33,810,479–33,810,649, 171 basesExon 72: 33,810,978–33,811,037, 60 basesExon 73: 33,812,863–33,812,994, 132 basesExon 74: 33,813,467–33,813,579, 113 basesExon 75: 33,816,862–33,816,958, 97 basesExon 76: 33,818,578–33,818,684, 107 basesExon 77: 33,819,756–33,819,807, 52 basesExon 78: 33,820,756–33,820,812, 57 basesExon 79: 33,821,270–33,821,369, 100 basesExon 80: 33,821,523–33,821,602, 80 basesExon 81: 33,822,996–33,823,072, 77 basesExon 82: 33,825,603–33,825,676, 74 basesExon 83: 33,826,252–33,826,269, 18 basesExon 84: 33,826,672–33,826,752, 81 basesExon 85: 33,827,199–33,827,287, 89 basesExon 86: 33,830,963–33,831,091, 129 basesExon 87: 33,834,968–33,835,072, 105 basesExon 88: 33,836,906–33,836,987, 82 basesExon 89: 33,837,631–33,838,958, 1,328 basesExon 90: 33,840,825–33,840,883, 59 basesExon 91: 33,841,864–33,842,035, 172 basesExon 92: 33,843,488–33,843,574, 87 basesExon 93: 33,844,862–33,845,062, 201 basesExon 94: 33,848,291–33,848,421, 131 basesExon 95: 33,853,045–33,853,087, 43 basesExon 96: 33,853,555–33,853,682, 128 basesExon 97: 33,854,389–33,854,449, 61 basesExon 98: 33,854,766–33,854,912, 147 basesExon 99: 33,857,780–33,857,914, 135 basesExon 100: 33,859,575–33,859,731, 157 basesExon 101: 33,860,595–33,860,659, 65 basesExon 102: 33,861,078–33,861,178, 101 basesExon 103: 33,864,138–33,864,189, 52 basesExon 104: 33,865,131–33,866,102, 972 bases11045′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 15.6 kb of the gene's 555.1 kb; 14,613 of those bases code for the protein.

How a genome test reads RYR3

2

positions in RYR3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 555.1 kb of RYR3, introns included, not only the 15.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RYR3 gene: ryanodine receptor 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/ryr3

Vancouver

Dante Labs. RYR3 gene: ryanodine receptor 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ryr3

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