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Trait

Broad ribs

Increased width of ribs

HPO HP:0000885

Summary

Also called
Wide ribs
Body system
Abnormality of the musculoskeletal system

25 genes linked to Broad ribs

Changes in these genes cause rare conditions in which Broad ribs is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
ARSKarylsulfatase family member KAlwaysIn 1 condition
IFT140intraflagellar transport 140AlwaysIn 1 condition
IL1RNinterleukin 1 receptor antagonistAlwaysIn 1 condition
PTDSS1phosphatidylserine synthase 1AlwaysIn 1 condition
PTH1Rparathyroid hormone 1 receptorAlwaysIn 1 condition
SERPINH1serpin family H member 1AlwaysIn 1 condition
TMEM53transmembrane protein 53AlwaysIn 1 condition
COL11A1collagen type XI alpha 1 chainVery often (80–99%)In 1 condition
COL11A2collagen type XI alpha 2 chainVery often (80–99%)In 1 condition
ABCC9ATP binding cassette subfamily C member 9Often (30–79%)In 1 condition
DYMdymeclinOften (30–79%)In 1 condition
KCNJ8potassium inwardly rectifying channel subfamily J member 8Often (30–79%)In 1 condition
NEK9NIMA related kinase 9Often (30–79%)In 1 condition
SETBP1SET binding protein 1Often (30–79%)In 2 conditions
SMAD4SMAD family member 4Often (30–79%)In 1 condition
TFE3transcription factor binding to IGHM enhancer 3Often (30–79%)In 1 condition
WNT7AWnt family member 7AOften (30–79%)In 1 condition
XYLT1xylosyltransferase 1Often (30–79%)In 1 condition
ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10Not recordedIn 1 condition
AMER1APC membrane recruitment protein 1Not recordedIn 1 condition
ARSBarylsulfatase BNot recordedIn 1 condition
ATP7AATPase copper transporting alphaNot recordedIn 1 condition
FBN1fibrillin 1Not recordedIn 1 condition
GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and betaNot recordedIn 1 condition
SOSTsclerostinNot recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Broader traits

Abnormality of the ribs

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

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