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Gene

IAPP

islet amyloid polypeptide

Summary

Cytogenetic location
12p12.1
Coordinates
Chromosome 12: 21,372,902–21,379,980 (GRCh38)
Exons
3 exons across 7.1 kb
Protein
89 amino acids
Also known as
AMYLIN, DAP, IAP
MANE Select transcript
ENST00000240652.8NM_000415.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads IAPP yet. The test sequences your whole genome, so your data includes it all the same.

How IAPP is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where IAPP sits. IAPP and 14 genes near it on chromosome 12, from 20,876,441 to 21,876,440.Chromosome 1212p12.1p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3321 Mb21.2 Mb21.4 Mb21.6 Mb21.8 MbSLCO1B3: 20,806,645–20,918,230, forward strandSLCO1B3SLCO1B3-SLCO1B7: 20,815,674–21,090,245, forward strandSLCO1B3-SLCO1B7: 21,047,179–21,176,895, forward strandSLCO1B1: 21,127,862–21,298,065, forward strandSLCO1B1SLCO1A2: 21,264,600–21,419,676, reverse strandSLCO1A2IAPP: 21,372,902–21,379,980, forward strandIAPPPYROXD1: 21,437,591–21,471,250, forward strandPYROXD1RECQL: 21,464,720–21,501,669, reverse strandRECQLGOLT1B: 21,501,781–21,518,408, forward strandGOLT1BSPX: 21,526,296–21,541,249, forward strandSPXGYS2: 21,531,545–21,604,951, reverse strandGYS2: 21,536,203–21,657,798, reverse strandLDHB: 21,635,339–21,757,890, reverse strandLDHBKCNJ8: 21,763,939–21,775,615, reverse strandKCNJ8ABCC9: 21,797,389–21,942,543, reverse strandABCC9Diagram of IAPP: 3 exons on the forward strand of chromosome 12Exon 1: 21,372,902–21,373,004, 103 basesExon 2: 21,373,337–21,373,431, 95 basesExon 3: 21,378,237–21,379,980, 1,744 bases1235′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.9 kb of the gene's 7.1 kb; 270 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). IAPP gene: islet amyloid polypeptide. Retrieved 17 October 2026, from https://dantelabs.com/genes/iapp

Vancouver

Dante Labs. IAPP gene: islet amyloid polypeptide [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/iapp

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