Trait
Abnormality of fingers or toes
Clinical name: Abnormal digit morphology
A morphological abnormality of a digit, i.e., of a finger or toe.
Summary
- Also called
- Abnormality of digit, Digital anomalies
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test15 genes linked to Abnormality of fingers or toes
Changes in these genes cause rare conditions in which Abnormality of fingers or toes is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CHSY1chondroitin sulfate synthase 1 | Very often (80–99%) | In 1 condition |
| LMX1BLIM homeobox transcription factor 1 beta | Very often (80–99%) | In 1 condition |
| FGF10fibroblast growth factor 10 | Often (30–79%) | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Often (30–79%) | In 1 condition |
| FGFR3fibroblast growth factor receptor 3 | Often (30–79%) | In 1 condition |
| GLMNglomulin, FKBP associated protein | Often (30–79%) | In 1 condition |
| FIG4FIG4 phosphoinositide 5-phosphatase | Sometimes (5–29%) | In 1 condition |
| FOXA2forkhead box A2 | Rarely (1–4%) | In 1 condition |
| GLI2GLI family zinc finger 2 | Rarely (1–4%) | In 1 condition |
| HESX1HESX homeobox 1 | Rarely (1–4%) | In 1 condition |
| LHX4LIM homeobox 4 | Rarely (1–4%) | In 1 condition |
| OTX2orthodenticle homeobox 2 | Rarely (1–4%) | In 1 condition |
| POU1F1POU class 1 homeobox 1 | Rarely (1–4%) | In 1 condition |
| PROP1PROP paired-like homeobox 1 | Rarely (1–4%) | In 1 condition |
| NSDHLNAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
- Curvature of digit201 genes
- Webbed fingers or toes159 genes
- Clubbing of fingers and toes103 genes
- More than five fingers or toes on hands or feet69 genes
- Oligodactyly28 genes
- Abnormalities of the fingers22 genes
- Short digit15 genes
- Abnormalities of the toes11 genes
- Wide digital bones10 genes
- Finger overgrowth4 genes
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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