Trait
Open angle glaucoma
A type of glaucoma defined by an open, normal appearing anterior chamber angle and raised intraocular pressure,
Summary
- Body system
- Abnormality of the eye
Reference genomeGRCh38hg38
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Get my Genome Test12 genes linked to Open angle glaucoma
Changes in these genes cause rare conditions in which Open angle glaucoma is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| EFEMP1EGF-like fibulin extracellular matrix protein 1 | Always | In 2 conditions |
| POLG2DNA polymerase gamma 2, accessory subunit | Always | In 1 condition |
| CYP1B1cytochrome P450 family 1 subfamily B member 1 | Often (30–79%) | In 1 condition |
| MYOCmyocilin | Often (30–79%) | In 1 condition |
| LMX1BLIM homeobox transcription factor 1 beta | Sometimes (5–29%) | In 1 condition |
| FGF10fibroblast growth factor 10 | Rarely (1–4%) | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Rarely (1–4%) | In 1 condition |
| FGFR3fibroblast growth factor receptor 3 | Rarely (1–4%) | In 1 condition |
| ASB10ankyrin repeat and SOCS box containing 10 | Not recorded | In 1 condition |
| NTF4neurotrophin 4 | Not recorded | In 1 condition |
| OPTNoptineurin | Not recorded | In 1 condition |
| WDR36WD repeat domain 36 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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