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Trait
Corneal ulceration
Disruption of the epithelial layer of the cornea with involvement of the underlying stroma.
Summary
- Also called
- Corneal ulcer, Corneal ulcerations
- Body system
- Abnormality of the eye
Corneal ulcerationHP:0012804
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Read the genes linked to Corneal ulceration, and the rest of your genome, with one test.
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Get my Genome Test36 genes linked to Corneal ulceration
Changes in these genes cause rare conditions in which Corneal ulceration is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| RIPK4receptor interacting serine/threonine kinase 4 | Always | In 1 condition |
| GSNgelsolin | Often (30–79%) | In 1 condition |
| LAMA3laminin subunit alpha 3 | Often (30–79%) | In 1 condition |
| MPV17mitochondrial inner membrane protein MPV17 | Often (30–79%) | In 1 condition |
| AAASaladin WD repeat nucleoporin | Sometimes (5–29%) | In 1 condition |
| ABCA12ATP binding cassette subfamily A member 12 | Sometimes (5–29%) | In 1 condition |
| AIREautoimmune regulator | Sometimes (5–29%) | In 1 condition |
| ALOX12Barachidonate 12-lipoxygenase, 12R type | Sometimes (5–29%) | In 1 condition |
| ALOXE3arachidonate epidermal lipoxygenase 3 | Sometimes (5–29%) | In 1 condition |
| ASPRV1aspartic peptidase retroviral like 1 | Sometimes (5–29%) | In 1 condition |
| CYP4F22cytochrome P450 family 4 subfamily F member 22 | Sometimes (5–29%) | In 1 condition |
| FGF10fibroblast growth factor 10 | Sometimes (5–29%) | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Sometimes (5–29%) | In 1 condition |
| FGFR3fibroblast growth factor receptor 3 | Sometimes (5–29%) | In 1 condition |
| GATA1GATA binding protein 1 | Sometimes (5–29%) | In 1 condition |
| GMPPAGDP-mannose pyrophosphorylase A | Sometimes (5–29%) | In 1 condition |
| LIPNlipase family member N | Sometimes (5–29%) | In 1 condition |
| NGLY1N-glycanase 1 | Sometimes (5–29%) | In 1 condition |
| NIPAL4NIPA like domain containing 4 | Sometimes (5–29%) | In 1 condition |
| SDR9C7short chain dehydrogenase/reductase family 9C member 7 | Sometimes (5–29%) | In 1 condition |
| SULT2B1sulfotransferase family 2B member 1 | Sometimes (5–29%) | In 1 condition |
| TGM1transglutaminase 1 | Sometimes (5–29%) | In 1 condition |
| TRAPPC11trafficking protein particle complex subunit 11 | Sometimes (5–29%) | In 1 condition |
| URODuroporphyrinogen decarboxylase | Sometimes (5–29%) | In 1 condition |
| UROSuroporphyrinogen III synthase | Sometimes (5–29%) | In 1 condition |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Rarely (1–4%) | In 1 condition |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Rarely (1–4%) | In 1 condition |
| LMNAlamin A/C | Rarely (1–4%) | In 1 condition |
| MTTPmicrosomal triglyceride transfer protein | Rarely (1–4%) | In 1 condition |
| NTRK1neurotrophic receptor tyrosine kinase 1 | Rarely (1–4%) | In 2 conditions |
| ZMPSTE24zinc metallopeptidase STE24 | Rarely (1–4%) | In 1 condition |
| ELP1elongator acetyltransferase complex subunit 1 | Not recorded | In 1 condition |
| FOXC2forkhead box C2 | Not recorded | In 1 condition |
| GJB2gap junction protein beta 2 | Not recorded | In 1 condition |
| KIFBPkinesin family binding protein | Not recorded | In 1 condition |
| PRDM12PR/SET domain 12 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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