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Trait
Quivering upper heart chambers resulting in irregular heartbeat
Clinical name: Atrial fibrillation
An atrial arrhythmia characterized by disorganized atrial activity without discrete P waves on the surface EKG, but instead by an undulating baseline or more sharply circumscribed atrial deflections of varying amplitude an frequency ranging from 350 to 600 per minute.
Summary
- Body system
- Abnormality of the cardiovascular system
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Read the genes linked to Quivering upper heart chambers resulting in irregular heartbeat, and the rest of your genome, with one test.
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Get my Genome Test77 genes linked to Quivering upper heart chambers resulting in irregular heartbeat
Changes in these genes cause rare conditions in which Quivering upper heart chambers resulting in irregular heartbeat is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| EMDemerin | Always | In 1 condition |
| GJA5gap junction protein alpha 5 | Always | In 2 conditions |
| KCNE2potassium voltage-gated channel subfamily E regulatory subunit 2 | Always | In 2 conditions |
| NPPAnatriuretic peptide A | Always | In 2 conditions |
| NUP155nucleoporin 155 | Always | In 2 conditions |
| SOX17SRY-box transcription factor 17 | Always | In 1 condition |
| ABCC9ATP binding cassette subfamily C member 9 | Often (30–79%) | In 1 condition |
| CACNA2D1calcium voltage-gated channel auxiliary subunit alpha2delta 1 | Often (30–79%) | In 1 condition |
| CORINcorin, serine peptidase | Often (30–79%) | In 1 condition |
| FLNCfilamin C | Often (30–79%) | In 2 conditions |
| GATA4GATA binding protein 4 | Often (30–79%) | In 2 conditions |
| GATA5GATA binding protein 5 | Often (30–79%) | In 2 conditions |
| GATA6GATA binding protein 6 | Often (30–79%) | In 2 conditions |
| GATAD1GATA zinc finger domain containing 1 | Often (30–79%) | In 1 condition |
| KCNA5potassium voltage-gated channel subfamily A member 5 | Often (30–79%) | In 1 condition |
| KCNE1potassium voltage-gated channel subfamily E regulatory subunit 1 | Often (30–79%) | In 1 condition |
| KCNH2potassium voltage-gated channel subfamily H member 2 | Often (30–79%) | In 1 condition |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Often (30–79%) | In 2 conditions |
| KCNJ3potassium inwardly rectifying channel subfamily J member 3 | Often (30–79%) | In 1 condition |
| KCNJ5potassium inwardly rectifying channel subfamily J member 5 | Often (30–79%) | In 1 condition |
| KCNQ1potassium voltage-gated channel subfamily Q member 1 | Often (30–79%) | In 4 conditions |
| LMNAlamin A/C | Often (30–79%) | In 3 conditions |
| MYH7myosin heavy chain 7 | Often (30–79%) | In 1 condition |
| MYL4myosin light chain 4 | Often (30–79%) | In 1 condition |
| NKX2-5NK2 homeobox 5 | Often (30–79%) | In 3 conditions |
| NKX2-6NK2 homeobox 6 | Often (30–79%) | In 1 condition |
| PITX2paired like homeodomain 2 | Often (30–79%) | In 1 condition |
| POPDC2popeye domain cAMP effector 2 | Often (30–79%) | In 1 condition |
| SCN1Bsodium voltage-gated channel beta subunit 1 | Often (30–79%) | In 1 condition |
| SCN2Bsodium voltage-gated channel beta subunit 2 | Often (30–79%) | In 1 condition |
| SCN3Bsodium voltage-gated channel beta subunit 3 | Often (30–79%) | In 1 condition |
| SCN4Bsodium voltage-gated channel beta subunit 4 | Often (30–79%) | In 2 conditions |
| SCN5Asodium voltage-gated channel alpha subunit 5 | Often (30–79%) | In 3 conditions |
| SLC4A3solute carrier family 4 member 3 | Often (30–79%) | In 1 condition |
| TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2 | Often (30–79%) | In 1 condition |
| TMEM43transmembrane protein 43 | Often (30–79%) | In 1 condition |
| TTNtitin | Often (30–79%) | In 2 conditions |
| ACTC1actin alpha cardiac muscle 1 | Sometimes (5–29%) | In 1 condition |
| ACTN2actinin alpha 2 | Sometimes (5–29%) | In 1 condition |
| APRTadenine phosphoribosyltransferase | Sometimes (5–29%) | In 1 condition |
Show 37 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| CAVIN1caveolae associated protein 1 | Sometimes (5–29%) | In 1 condition |
| CITED2Cbp/p300 interacting transactivator with ED-rich tail 2 | Sometimes (5–29%) | In 2 conditions |
| DBHdopamine beta-hydroxylase | Sometimes (5–29%) | In 1 condition |
| DMPKDM1 protein kinase | Sometimes (5–29%) | In 1 condition |
| FHOD3formin homology 2 domain containing 3 | Sometimes (5–29%) | In 1 condition |
| KIF20Akinesin family member 20A | Sometimes (5–29%) | In 1 condition |
| MFAP5microfibril associated protein 5 | Sometimes (5–29%) | In 1 condition |
| MYH6myosin heavy chain 6 | Sometimes (5–29%) | In 1 condition |
| MYOZ2myozenin 2 | Sometimes (5–29%) | In 1 condition |
| MYPNmyopalladin | Sometimes (5–29%) | In 2 conditions |
| NEXNnexilin F-actin binding protein | Sometimes (5–29%) | In 1 condition |
| POLGDNA polymerase gamma, catalytic subunit | Sometimes (5–29%) | In 1 condition |
| POLG2DNA polymerase gamma 2, accessory subunit | Sometimes (5–29%) | In 1 condition |
| PRKAG2protein kinase AMP-activated non-catalytic subunit gamma 2 | Sometimes (5–29%) | In 1 condition |
| PSEN2presenilin 2 | Sometimes (5–29%) | In 1 condition |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Sometimes (5–29%) | In 1 condition |
| SGO1shugoshin 1 | Sometimes (5–29%) | In 1 condition |
| SLC25A4solute carrier family 25 member 4 | Sometimes (5–29%) | In 1 condition |
| SMAD3SMAD family member 3 | Sometimes (5–29%) | In 2 conditions |
| TBX20T-box transcription factor 20 | Sometimes (5–29%) | In 1 condition |
| TLL1tolloid like 1 | Sometimes (5–29%) | In 3 conditions |
| TNNC1troponin C1, slow skeletal and cardiac type | Sometimes (5–29%) | In 1 condition |
| TNNI3troponin I3, cardiac type | Sometimes (5–29%) | In 2 conditions |
| TNNT2troponin T2, cardiac type | Sometimes (5–29%) | In 2 conditions |
| TPM1tropomyosin 1 | Sometimes (5–29%) | In 1 condition |
| TRIM63tripartite motif containing 63 | Sometimes (5–29%) | In 1 condition |
| TWNKtwinkle mtDNA helicase | Sometimes (5–29%) | In 1 condition |
| XKX-linked Kx blood group antigen, Kell and VPS13A binding protein | Sometimes (5–29%) | In 1 condition |
| MT-CYBmitochondrially encoded cytochrome b | Rarely (1–4%) | In 1 condition |
| ANK2ankyrin 2 | Not recorded | In 1 condition |
| CACNA1Ccalcium voltage-gated channel subunit alpha1 C | Not recorded | In 1 condition |
| CACNB2calcium voltage-gated channel auxiliary subunit beta 2 | Not recorded | In 1 condition |
| DTNAdystrobrevin alpha | Not recorded | In 1 condition |
| HCN4hyperpolarization activated cyclic nucleotide gated potassium channel 4 | Not recorded | In 1 condition |
| PLNphospholamban | Not recorded | In 1 condition |
| TNNI3KTNNI3 interacting kinase | Not recorded | In 1 condition |
| ZFHX3zinc finger homeobox 3 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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