Trait
Neck flexion weakness
Clinical name: Neck flexor weakness
Weakness of the muscles involved in neck flexion (sternocleidomastoid, longus capitus, longus colli, and scalenus anterior).
Summary
- Also called
- Neck flexor muscle weakness
- Body system
- Abnormality of the musculoskeletal system
Reference genomeGRCh38hg38
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Get my Genome Test44 genes linked to Neck flexion weakness
Changes in these genes cause rare conditions in which Neck flexion weakness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ACTA1actin alpha 1, skeletal muscle | Always | In 3 conditions |
| CAV3caveolin 3 | Always | In 1 condition |
| COL6A2collagen type VI alpha 2 chain | Always | In 1 condition |
| COL6A3collagen type VI alpha 3 chain | Always | In 1 condition |
| HSPB8heat shock protein family B (small) member 8 | Always | In 1 condition |
| MEGF10multiple EGF like domains 10 | Always | In 1 condition |
| SELENONselenoprotein N | Always | In 1 condition |
| TOP3ADNA topoisomerase III alpha | Always | In 1 condition |
| CFL2cofilin 2 | Often (30–79%) | In 1 condition |
| CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 | Often (30–79%) | In 2 conditions |
| GYG1glycogenin 1 | Often (30–79%) | In 1 condition |
| KLHL41kelch like family member 41 | Often (30–79%) | In 1 condition |
| LMOD3leiomodin 3 | Often (30–79%) | In 1 condition |
| NEBnebulin | Often (30–79%) | In 3 conditions |
| POLGDNA polymerase gamma, catalytic subunit | Often (30–79%) | In 1 condition |
| TPM2tropomyosin 2 | Often (30–79%) | In 1 condition |
| TTNtitin | Often (30–79%) | In 2 conditions |
| ALS2alsin Rho guanine nucleotide exchange factor ALS2 | Sometimes (5–29%) | In 1 condition |
| ATP13A2ATPase cation transporting 13A2 | Sometimes (5–29%) | In 1 condition |
| DESdesmin | Sometimes (5–29%) | In 1 condition |
| DYSFdysferlin | Sometimes (5–29%) | In 1 condition |
| ERLIN1ER lipid raft associated 1 | Sometimes (5–29%) | In 1 condition |
| FUSFUS RNA binding protein | Sometimes (5–29%) | In 1 condition |
| GNEglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | Sometimes (5–29%) | In 1 condition |
| LAMA2laminin subunit alpha 2 | Sometimes (5–29%) | In 1 condition |
| MYH7myosin heavy chain 7 | Sometimes (5–29%) | In 1 condition |
| RNASEH1ribonuclease H1 | Sometimes (5–29%) | In 1 condition |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Sometimes (5–29%) | In 1 condition |
| SGCGsarcoglycan gamma | Sometimes (5–29%) | In 1 condition |
| SIGMAR1sigma receptor chaperone 1 | Sometimes (5–29%) | In 1 condition |
| SORDsorbitol dehydrogenase | Sometimes (5–29%) | In 1 condition |
| SPG11SPG11 vesicle trafficking associated, spatacsin | Sometimes (5–29%) | In 1 condition |
| SPTLC1serine palmitoyltransferase long chain base subunit 1 | Sometimes (5–29%) | In 1 condition |
| SPTLC2serine palmitoyltransferase long chain base subunit 2 | Sometimes (5–29%) | In 1 condition |
| SYNE1spectrin repeat containing nuclear envelope protein 1 | Sometimes (5–29%) | In 1 condition |
| TARDBPTAR DNA binding protein | Sometimes (5–29%) | In 1 condition |
| TNNT1troponin T1, slow skeletal type | Sometimes (5–29%) | In 1 condition |
| TRMT2BtRNA methyltransferase 2B | Sometimes (5–29%) | In 1 condition |
| UBQLN2ubiquilin 2 | Sometimes (5–29%) | In 1 condition |
| FLNCfilamin C | Rarely (1–4%) | In 1 condition |
Show 4 more genes
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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