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Gene

PLIN4

perilipin 4

Summary

Cytogenetic location
19p13.3
Coordinates
Chromosome 19: 4,502,192–4,518,486 (GRCh38)
Exons
8 exons across 16.3 kb
Protein
1,371 amino acids
Also known as
S3-12
Previous symbols
KIAA1881
MANE Select transcript
ENST00000301286.5NM_001367868.2
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads PLIN4 yet. The test sequences your whole genome, so your data includes it all the same.

How PLIN4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 19, with a bracket where PLIN4 sits. PLIN4 and 30 genes near it on chromosome 19, from 4,010,339 to 5,010,338.Chromosome 1919p13.3p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.434.2 Mb4.4 Mb4.6 Mb4.8 Mb5 MbPIAS4: 4,007,690–4,039,386, forward strandPIAS4ZBTB7A: 4,041,419–4,067,636, reverse strandZBTB7AMAP2K2: 4,090,316–4,124,238, reverse strandMAP2K2CREB3L3: 4,152,949–4,173,057, forward strandCREB3L3SIRT6: 4,174,104–4,182,604, reverse strandSIRT6ANKRD24: 4,182,630–4,224,818, forward strandANKRD24EBI3: 4,229,267–4,238,167, forward strandEBI3YJU2: 4,247,062–4,269,091, forward strandYJU2SHD: 4,279,013–4,290,728, forward strandSHDTMIGD2: 4,292,227–4,302,431, reverse strandTMIGD2FSD1: 4,304,587–4,323,844, forward strandFSD1STAP2: 4,324,040–4,342,786, reverse strandSTAP2MPND: 4,343,527–4,360,086, forward strandMPNDSH3GL1: 4,360,367–4,400,573, reverse strandSH3GL1CHAF1A: 4,402,522–4,445,018, forward strandCHAF1AUBXN6: 4,444,999–4,457,794, reverse strandUBXN6HDGFL2: 4,472,244–4,502,225, forward strandHDGFL2PLIN4: 4,502,192–4,518,486, reverse strandPLIN4PLIN5: 4,522,527–4,535,285, reverse strandPLIN5: 4,528,427–4,540,067, reverse strandLRG1: 4,536,402–4,540,104, reverse strandLRG1SEMA6B: 4,542,588–4,581,795, reverse strandTIPE1: 4,639,503–4,655,568, forward strandTIPE1MYDGF: 4,641,374–4,670,403, reverse strandMYDGFDPP9: 4,674,341–4,724,673, reverse strandDPP9FEM1A: 4,791,734–4,801,273, forward strandFEM1ATICAM1: 4,815,932–4,831,749, reverse strandTICAM1PLIN3: 4,838,334–4,867,717, reverse strandPLIN3ARRDC5: 4,890,437–4,902,948, reverse strandARRDC5UHRF1: 4,903,080–4,962,154, forward strandUHRF1KDM4B: 4,969,106–5,153,611, forward strandKDM4BDiagram of PLIN4: 8 exons on the reverse strand of chromosome 19Exon 5: 1 known disease-causing siteExon 8: 4,502,192–4,504,785, 2,594 basesExon 7: 4,504,861–4,504,947, 87 basesExon 6: 4,508,768–4,508,955, 188 basesExon 5: 4,510,446–4,513,701, 3,256 basesExon 4: 4,516,617–4,516,678, 62 basesExon 3: 4,517,554–4,517,698, 145 basesExon 2: 4,518,222–4,518,289, 68 basesExon 1: 4,518,385–4,518,486, 102 bases8515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.5 kb of the gene's 16.3 kb; 4,116 of those bases code for the protein.

Sequencing PLIN4

12Moderate

How hard PLIN4 is to sequence with short reads, out of 100

  • Mappability3.8%
  • Homology0%
  • Repeats41%
  • GC content42%
  • Reference coverage0%

2

positions in PLIN4 where ClinVar classes a change as pathogenic or likely pathogenic

1 of them (50%) falls in a region short reads find hard.

  • Low mappability (1 site)

A whole genome covers all 16.3 kb of PLIN4, introns included, not only the 6.5 kb of exons.

Traits linked to PLIN4

The Human Phenotype Ontology lists these as features of the rare conditions PLIN4 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

Cite this page

APA

Dante Labs. (n.d.). PLIN4 gene: perilipin 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/plin4

Vancouver

Dante Labs. PLIN4 gene: perilipin 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/plin4

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