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Gene

DPH5

diphthamide biosynthesis 5

Summary

Cytogenetic location
1p21.2
Coordinates
Chromosome 1: 100,989,623–101,025,784 (GRCh38)
Exons
8 exons across 36.2 kb
Protein
285 amino acids
Also known as
CGI-30
MANE Select transcript
ENST00000370109.8NM_015958.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DPH5 yet. The test sequences your whole genome, so your data includes it all the same.

How DPH5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 1, with a bracket where DPH5 sits. DPH5 and 6 genes near it on chromosome 1, from 100,507,704 to 101,507,703.Chromosome 11p21.2p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44100.6 Mb100.8 Mb101 Mb101.2 Mb101.4 MbCDC14A: 100,325,629–100,520,564, forward strandCDC14AGPR88: 100,538,105–100,542,021, forward strandGPR88VCAM1: 100,719,684–100,739,045, forward strandVCAM1EXTL2: 100,871,371–100,896,000, reverse strandEXTL2SLC30A7: 100,896,061–100,996,627, forward strandSLC30A7DPH5: 100,989,623–101,025,784, reverse strandDPH5S1PR1: 101,235,366–101,243,749, forward strandS1PR1Diagram of DPH5: 8 exons on the reverse strand of chromosome 1Exon 8: 1 known disease-causing siteExon 8: 100,989,623–100,990,631, 1,009 basesExon 7: 100,992,637–100,992,740, 104 basesExon 6: 100,995,110–100,995,149, 40 basesExon 5: 101,001,467–101,001,587, 121 basesExon 4: 101,013,710–101,013,818, 109 basesExon 3: 101,021,641–101,021,765, 125 basesExon 2: 101,025,309–101,025,466, 158 basesExon 1: 101,025,683–101,025,784, 102 bases8515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.8 kb of the gene's 36.2 kb; 858 of those bases code for the protein.

How a genome test reads DPH5

2

positions in DPH5 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 36.2 kb of DPH5, introns included, not only the 1.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DPH5 gene: diphthamide biosynthesis 5. Retrieved 16 October 2026, from https://dantelabs.com/genes/dph5

Vancouver

Dante Labs. DPH5 gene: diphthamide biosynthesis 5 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dph5

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