Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
Trait
Loss of bowel control
Clinical name: Bowel incontinence
Involuntary fecal soiling in adults and children who have usually already been toilet trained.
Summary
- Also called
- Anal incontinence, Faecal incontinence, Fecal incontinence
Loss of bowel controlHP:0002607
Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
Read the genes linked to Loss of bowel control, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test47 genes linked to Loss of bowel control
Changes in these genes cause rare conditions in which Loss of bowel control is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| HTRA1HtrA serine peptidase 1 | Always | In 1 condition |
| KYkyphoscoliosis peptidase | Always | In 1 condition |
| FUZfuzzy planar cell polarity protein | Very often (80–99%) | In 1 condition |
| VANGL1VANGL planar cell polarity protein 1 | Very often (80–99%) | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Often (30–79%) | In 2 conditions |
| DSTYKdual serine/threonine and tyrosine protein kinase | Often (30–79%) | In 1 condition |
| PLP1proteolipid protein 1 | Often (30–79%) | In 1 condition |
| SLC44A1solute carrier family 44 member 1 | Often (30–79%) | In 1 condition |
| ZEB2zinc finger E-box binding homeobox 2 | Often (30–79%) | In 2 conditions |
| ARSAarylsulfatase A | Sometimes (5–29%) | In 1 condition |
| ARVCFARVCF delta catenin family member | Sometimes (5–29%) | In 1 condition |
| ATP13A2ATPase cation transporting 13A2 | Sometimes (5–29%) | In 1 condition |
| BCRBCR activator of RhoGEF and GTPase | Sometimes (5–29%) | In 1 condition |
| COMTcatechol-O-methyltransferase | Sometimes (5–29%) | In 1 condition |
| CRKLCRK like proto-oncogene, adaptor protein | Sometimes (5–29%) | In 1 condition |
| DACT1dishevelled binding antagonist of beta catenin 1 | Sometimes (5–29%) | In 1 condition |
| DDHD2DDHD domain containing 2 | Sometimes (5–29%) | In 1 condition |
| EIF2AK2eukaryotic translation initiation factor 2 alpha kinase 2 | Sometimes (5–29%) | In 1 condition |
| FA2Hfatty acid 2-hydroxylase | Sometimes (5–29%) | In 1 condition |
| FGFR3fibroblast growth factor receptor 3 | Sometimes (5–29%) | In 1 condition |
| FMR1fragile X messenger ribonucleoprotein 1 | Sometimes (5–29%) | In 2 conditions |
| GP1BBglycoprotein Ib platelet subunit beta | Sometimes (5–29%) | In 1 condition |
| HIRAhistone cell cycle regulator | Sometimes (5–29%) | In 1 condition |
| HPS6HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 | Sometimes (5–29%) | In 1 condition |
| HPSE2heparanase 2 (inactive) | Sometimes (5–29%) | In 1 condition |
| ISL1ISL LIM homeobox 1 | Sometimes (5–29%) | In 1 condition |
| JMJD1Cjumonji domain containing 1C | Sometimes (5–29%) | In 1 condition |
| LRIG2leucine rich repeats and immunoglobulin like domains 2 | Sometimes (5–29%) | In 1 condition |
| MAPK1mitogen-activated protein kinase 1 | Sometimes (5–29%) | In 1 condition |
| PSAPprosaposin | Sometimes (5–29%) | In 1 condition |
| RREB1ras responsive element binding protein 1 | Sometimes (5–29%) | In 1 condition |
| RTN2reticulon 2 | Sometimes (5–29%) | In 1 condition |
| SALL1spalt like transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| SCN4Asodium voltage-gated channel alpha subunit 4 | Sometimes (5–29%) | In 1 condition |
| SEC24CSEC24 homolog C, COPII component | Sometimes (5–29%) | In 1 condition |
| SIsucrase-isomaltase | Sometimes (5–29%) | In 1 condition |
| TBCDtubulin folding cofactor D | Sometimes (5–29%) | In 2 conditions |
| TBX1T-box transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| TP63tumor protein p63 | Sometimes (5–29%) | In 1 condition |
| UBAP1ubiquitin associated protein 1 | Sometimes (5–29%) | In 1 condition |
Show 7 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Sometimes (5–29%) | In 1 condition |
| VCPvalosin containing protein | Sometimes (5–29%) | In 1 condition |
| FLVCR1FLVCR choline and heme transporter 1 | Rarely (1–4%) | In 1 condition |
| NOP56NOP56 ribonucleoprotein | Rarely (1–4%) | In 1 condition |
| CFAP43cilia and flagella associated protein 43 | Not recorded | In 1 condition |
| SLC9A6solute carrier family 9 member A6 | Not recorded | In 1 condition |
| ZFYVE26zinc finger FYVE-type containing 26 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks