Trait
Dark urine
An abnormal dark color of the urine.
Summary
Reference genomeGRCh38hg38
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Get my Genome Test16 genes linked to Dark urine
Changes in these genes cause rare conditions in which Dark urine is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ATP11CATPase phospholipid transporting 11C (ATP11C blood group) | Always | In 1 condition |
| HGDhomogentisate 1,2-dioxygenase | Always | In 2 conditions |
| LPIN1lipin 1 | Very often (80–99%) | In 1 condition |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Very often (80–99%) | In 1 condition |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Very often (80–99%) | In 1 condition |
| OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | Very often (80–99%) | In 1 condition |
| AKR1D1aldo-keto reductase family 1 member D1 | Often (30–79%) | In 1 condition |
| CPOXcoproporphyrinogen oxidase | Often (30–79%) | In 1 condition |
| MPV17mitochondrial inner membrane protein MPV17 | Often (30–79%) | In 1 condition |
| PYGMglycogen phosphorylase, muscle associated | Often (30–79%) | In 2 conditions |
| HMBShydroxymethylbilane synthase | Sometimes (5–29%) | In 1 condition |
| IFT56intraflagellar transport 56 | Sometimes (5–29%) | In 1 condition |
| IRAK1interleukin 1 receptor associated kinase 1 | Sometimes (5–29%) | In 1 condition |
| SAT1spermidine/spermine N1-acetyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| SPP1secreted phosphoprotein 1 | Sometimes (5–29%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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