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Gene

C3orf52

chromosome 3 open reading frame 52

Summary

Cytogenetic location
3q13.2
Coordinates
Chromosome 3: 112,086,389–112,118,210 (GRCh38)
Exons
6 exons across 31.8 kb
Protein
217 amino acids
Also known as
FLJ23186, TTMP
MANE Select transcript
ENST00000264848.10NM_024616.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

How C3orf52 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 3, with a bracket where C3orf52 sits. C3orf52 and 13 genes near it on chromosome 3, from 111,602,300 to 112,602,299.Chromosome 33q13.2p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q29111.8 Mb112 Mb112.2 Mb112.4 Mb112.6 MbCD96: 111,292,719–111,680,594, forward strandCD96PLCXD2: 111,674,655–111,846,447, forward strandPLCXD2PHLDB2: 111,732,403–111,976,837, forward strandPHLDB2ABHD10: 111,978,972–111,993,368, forward strandABHD10TAGLN3: 111,998,735–112,013,890, forward strandTAGLN3TMPRSS7: 112,034,736–112,081,269, forward strandTMPRSS7C3orf52: 112,086,389–112,118,210, forward strandC3orf52GCSAM: 112,120,839–112,133,270, reverse strandGCSAMSLC9C1: 112,140,898–112,294,227, reverse strandSLC9C1CD200: 112,332,235–112,363,181, forward strandCD200BTLA: 112,461,067–112,499,668, reverse strandBTLAATG3: 112,531,772–112,562,318, reverse strandATG3SLC35A5: 112,561,269–112,587,350, forward strandSLC35A5CCDC80: 112,596,797–112,649,530, reverse strandCCDC80Diagram of C3orf52: 6 exons on the forward strand of chromosome 3Exon 1: 1 known disease-causing siteExon 4: 1 known disease-causing siteExon 1: 112,086,389–112,086,545, 157 basesExon 2: 112,093,360–112,093,489, 130 basesExon 3: 112,102,838–112,102,965, 128 basesExon 4: 112,109,543–112,109,613, 71 basesExon 5: 112,112,964–112,113,145, 182 basesExon 6: 112,116,642–112,118,210, 1,569 bases1234565′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.2 kb of the gene's 31.8 kb; 654 of those bases code for the protein.

How a genome test reads C3orf52

2

positions in C3orf52 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 31.8 kb of C3orf52, introns included, not only the 2.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). C3orf52 gene: chromosome 3 open reading frame 52. Retrieved 17 October 2026, from https://dantelabs.com/genes/c3orf52

Vancouver

Dante Labs. C3orf52 gene: chromosome 3 open reading frame 52 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/c3orf52

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