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Gene

DAGLA

diacylglycerol lipase alpha

Summary

Cytogenetic location
11q12.2
Coordinates
Chromosome 11: 61,680,391–61,747,001 (GRCh38)
Exons
20 exons across 66.6 kb
Protein
1,042 amino acids
Also known as
KIAA0659, NSDDR, DAGLALPHA
Previous symbols
C11orf11
MANE Select transcript
ENST00000257215.10NM_006133.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DAGLA yet. The test sequences your whole genome, so your data includes it all the same.

How DAGLA is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where DAGLA sits. DAGLA and 26 genes near it on chromosome 11, from 61,213,696 to 62,213,695.Chromosome 1111q12.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2561.4 Mb61.6 Mb61.8 Mb62 Mb62.2 MbPGA4: 61,222,347–61,231,694, forward strandPGA4PGA5: 61,241,175–61,251,444, forward strandPGA5VWCE: 61,255,672–61,295,553, reverse strandVWCEDDB1: 61,299,447–61,342,596, reverse strandDDB1TKFC: 61,333,205–61,354,339, forward strandTKFCCYB561A3: 61,348,453–61,362,343, reverse strandCYB561A3TMEM138: 61,361,964–61,377,890, forward strandTMEM138TMEM216: 61,392,393–61,400,408, forward strandTMEM216CPSF7: 61,402,641–61,430,105, reverse strandCPSF7: 61,429,220–61,485,822, forward strandSDHAF2: 61,430,032–61,473,614, forward strandSDHAF2SAXO4: 61,481,120–61,490,931, forward strandSAXO4LRRC10B: 61,508,749–61,511,018, forward strandLRRC10BSYT7: 61,513,714–61,581,201, reverse strandSYT7DAGLA: 61,680,391–61,747,001, forward strandDAGLAMYRF: 61,752,593–61,788,518, forward strandMYRFTMEM258: 61,768,455–61,792,802, reverse strandTMEM258FEN1: 61,792,725–61,797,238, forward strandFEN1FADS2: 61,792,980–61,867,354, forward strandFADS1: 61,799,624–61,829,318, reverse strandFADS1FADS3: 61,873,515–61,892,136, reverse strandFADS3RAB3IL1: 61,897,232–61,920,289, reverse strandRAB3IL1BEST1: 61,949,808–61,965,515, forward strandBEST1FTH1: 61,959,718–61,967,640, reverse strandFTH1INCENP: 62,123,985–62,155,474, forward strandINCENPSCGB1D1: 62,190,216–62,193,539, forward strandSCGB1D1SCGB2A1: 62,208,666–62,213,943, forward strandSCGB2A1Diagram of DAGLA: 20 exons on the forward strand of chromosome 11Exon 20: 1 known disease-causing siteExon 1: 61,680,391–61,680,504, 114 basesExon 2: 61,720,112–61,720,250, 139 basesExon 3: 61,720,679–61,720,890, 212 basesExon 4: 61,722,859–61,722,960, 102 basesExon 5: 61,723,434–61,723,572, 139 basesExon 6: 61,725,995–61,726,082, 88 basesExon 7: 61,728,153–61,728,287, 135 basesExon 8: 61,728,931–61,729,008, 78 basesExon 9: 61,731,317–61,731,441, 125 basesExon 10: 61,734,849–61,735,002, 154 basesExon 11: 61,735,561–61,735,644, 84 basesExon 12: 61,735,739–61,735,816, 78 basesExon 13: 61,736,270–61,736,350, 81 basesExon 14: 61,737,182–61,737,324, 143 basesExon 15: 61,737,687–61,737,755, 69 basesExon 16: 61,738,135–61,738,207, 73 basesExon 17: 61,739,465–61,739,661, 197 basesExon 18: 61,740,463–61,740,592, 130 basesExon 19: 61,741,162–61,741,349, 188 basesExon 20: 61,743,532–61,747,001, 3,470 bases151015205′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.8 kb of the gene's 66.6 kb; 3,129 of those bases code for the protein.

How a genome test reads DAGLA

1

position in DAGLA where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 66.6 kb of DAGLA, introns included, not only the 5.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DAGLA gene: diacylglycerol lipase alpha. Retrieved 17 October 2026, from https://dantelabs.com/genes/dagla

Vancouver

Dante Labs. DAGLA gene: diacylglycerol lipase alpha [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dagla

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