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Gene

SIPA1

signal-induced proliferation-associated 1

Summary

Cytogenetic location
11q13.1
Coordinates
Chromosome 11: 65,638,101–65,650,912 (GRCh38)
Exons
16 exons across 12.8 kb
Protein
1,042 amino acids
Also known as
SPA1
MANE Select transcript
ENST00000534313.6NM_006747.4
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SIPA1 yet. The test sequences your whole genome, so your data includes it all the same.

How SIPA1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 11, with a bracket where SIPA1 sits. SIPA1 and 42 genes near it on chromosome 11, from 65,144,507 to 66,144,506.Chromosome 1111q13.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2565.2 Mb65.4 Mb65.6 Mb65.8 Mb66 MbSYVN1: 65,121,780–65,146,912, reverse strandSYVN1SPDYC: 65,166,137–65,173,380, forward strandSPDYCCAPN1: 65,180,566–65,212,006, forward strandCAPN1POLA2: 65,261,835–65,305,959, forward strandPOLA2: 65,261,928–65,326,543, forward strandCDC42EP2: 65,298,955–65,322,662, forward strandCDC42EP2DPF2: 65,333,792–65,354,262, forward strandDPF2TIGD3: 65,354,746–65,357,613, forward strandTIGD3SLC25A45: 65,375,186–65,384,550, reverse strandSLC25A45FRMD8: 65,386,592–65,413,526, forward strandFRMD8SCYL1: 65,525,044–65,538,711, forward strandSCYL1LTBP3: 65,538,556–65,558,930, reverse strandZNRD2: 65,570,459–65,574,203, forward strandZNRD2FAM89B: 65,572,349–65,574,199, forward strandEHBP1L1: 65,575,943–65,594,089, forward strandKCNK7: 65,592,836–65,595,996, reverse strandKCNK7MAP3K11: 65,597,149–65,615,382, reverse strandMAP3K11PCNX3: 65,615,742–65,637,441, forward strandPCNX3SIPA1: 65,638,101–65,650,912, forward strandSIPA1RELA: 65,653,599–65,663,138, reverse strandRELAKAT5: 65,711,992–65,719,604, forward strandKAT5RNASEH2C: 65,713,901–65,720,988, reverse strandRNASEH2CAP5B1: 65,772,723–65,781,708, reverse strandAP5B1OVOL1: 65,786,714–65,797,219, forward strandOVOL1CFL1: 65,823,022–65,862,026, reverse strandCFL1SNX32: 65,833,664–65,856,896, forward strandSNX32MUS81: 65,857,126–65,867,653, forward strandMUS81EFEMP2: 65,866,300–65,878,497, reverse strandEFEMP2CTSW: 65,879,809–65,883,741, forward strandFIBP: 65,883,740–65,888,532, reverse strandCCDC85B: 65,890,673–65,891,635, forward strandFOSL1: 65,892,049–65,900,573, reverse strandC11orf68: 65,916,810–65,919,137, reverse strandDRAP1: 65,919,258–65,921,565, forward strandDRAP1TSGA10IP: 65,945,480–65,960,217, forward strandTSGA10IPSART1: 65,961,681–65,980,137, forward strandSART1EIF1AD: 65,992,009–66,002,472, reverse strandEIF1ADBANF1: 66,001,832–66,004,170, forward strandBANF1CST6: 66,011,506–66,013,505, forward strandCATSPER1: 66,016,752–66,026,479, reverse strandGAL3ST3: 66,040,748–66,049,502, reverse strandGAL3ST3SF3B2: 66,050,729–66,069,308, forward strandSF3B2PACS1: 66,070,017–66,248,638, forward strandPACS1Diagram of SIPA1: 16 exons on the forward strand of chromosome 11Exon 1: 65,638,101–65,638,182, 82 basesExon 2: 65,640,831–65,641,600, 770 basesExon 3: 65,642,250–65,642,377, 128 basesExon 4: 65,642,463–65,642,639, 177 basesExon 5: 65,644,955–65,645,129, 175 basesExon 6: 65,645,854–65,645,957, 104 basesExon 7: 65,646,221–65,646,378, 158 basesExon 8: 65,646,456–65,647,065, 610 basesExon 9: 65,647,384–65,647,658, 275 basesExon 10: 65,649,262–65,649,480, 219 basesExon 11: 65,649,561–65,649,672, 112 basesExon 12: 65,649,757–65,649,865, 109 basesExon 13: 65,649,950–65,650,051, 102 basesExon 14: 65,650,138–65,650,192, 55 basesExon 15: 65,650,401–65,650,479, 79 basesExon 16: 65,650,569–65,650,912, 344 bases12468101214165′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.5 kb of the gene's 12.8 kb; 3,129 of those bases code for the protein.

How a genome test reads SIPA1

1

position in SIPA1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 12.8 kb of SIPA1, introns included, not only the 3.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SIPA1 gene: signal-induced proliferation-associated 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/sipa1

Vancouver

Dante Labs. SIPA1 gene: signal-induced proliferation-associated 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/sipa1

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