Trait
Birth weight > 90th percentile
Clinical name: Large for gestational age
The term large for gestational age applies to babies whose birth weight lies above the 90th percentile for that gestational age.
Summary
- Also called
- Birthweight > 90th percentile, Fetal macrosomia, Foetal macrosomia, Macrosomia, Macrosomia, neonatal
- Body system
- Growth abnormality
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Birth weight > 90th percentile, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test54 genes linked to Birth weight > 90th percentile
Changes in these genes cause rare conditions in which Birth weight > 90th percentile is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| EDNRBendothelin receptor type B | Always | In 1 condition |
| HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | Always | In 2 conditions |
| HNF4Ahepatocyte nuclear factor 4 alpha | Always | In 3 conditions |
| IFT74intraflagellar transport 74 | Always | In 1 condition |
| NSD1nuclear receptor binding SET domain protein 1 | Always | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Always | In 1 condition |
| SPIN4spindlin family member 4 | Always | In 1 condition |
| AKT2AKT serine/threonine kinase 2 | Very often (80–99%) | In 2 conditions |
| DIS3L2DIS3 like 3'-5' exoribonuclease 2 | Very often (80–99%) | In 1 condition |
| PTCH1patched 1 | Very often (80–99%) | In 1 condition |
| RNF135ring finger protein 135 | Very often (80–99%) | In 1 condition |
| ABCC8ATP binding cassette subfamily C member 8 | Often (30–79%) | In 3 conditions |
| BIN1bridging integrator 1 | Often (30–79%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Often (30–79%) | In 1 condition |
| DICER1dicer 1, ribonuclease III | Often (30–79%) | In 1 condition |
| DLK1delta like non-canonical Notch ligand 1 | Often (30–79%) | In 2 conditions |
| DNM2dynamin 2 | Often (30–79%) | In 1 condition |
| FIBPFGF1 intracellular binding protein | Often (30–79%) | In 2 conditions |
| HNF1AHNF1 homeobox A | Often (30–79%) | In 2 conditions |
| KCNJ11potassium inwardly rectifying channel subfamily J member 11 | Often (30–79%) | In 4 conditions |
| MEG3maternally expressed 3 | Often (30–79%) | In 2 conditions |
| MTMR14myotubularin related protein 14 | Often (30–79%) | In 1 condition |
| MTORmechanistic target of rapamycin kinase | Often (30–79%) | In 2 conditions |
| MYF6myogenic factor 6 | Often (30–79%) | In 1 condition |
| NDST1N-deacetylase and N-sulfotransferase 1 | Often (30–79%) | In 1 condition |
| ODC1ornithine decarboxylase 1 | Often (30–79%) | In 2 conditions |
| PTENphosphatase and tensin homolog | Often (30–79%) | In 1 condition |
| RIT1Ras like without CAAX 1 | Often (30–79%) | In 1 condition |
| RTL1retrotransposon Gag like 1 | Often (30–79%) | In 2 conditions |
| RYR1ryanodine receptor 1 | Often (30–79%) | In 1 condition |
| SHOC2SHOC2 leucine rich repeat scaffold protein | Often (30–79%) | In 1 condition |
| SOS1SOS Ras/Rac guanine nucleotide exchange factor 1 | Often (30–79%) | In 1 condition |
| UCP2uncoupling protein 2 | Often (30–79%) | In 1 condition |
| ANK3ankyrin 3 | Sometimes (5–29%) | In 1 condition |
| APPL1adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 | Sometimes (5–29%) | In 1 condition |
| BLKBLK proto-oncogene, Src family tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| CELcarboxyl ester lipase | Sometimes (5–29%) | In 1 condition |
| EHMT1euchromatic histone lysine methyltransferase 1 | Sometimes (5–29%) | In 2 conditions |
| GCKglucokinase | Sometimes (5–29%) | In 1 condition |
| GLI3GLI family zinc finger 3 | Sometimes (5–29%) | In 1 condition |
Show 14 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| INSinsulin | Sometimes (5–29%) | In 1 condition |
| KLF11KLF transcription factor 11 | Sometimes (5–29%) | In 1 condition |
| KMT2Clysine methyltransferase 2C | Sometimes (5–29%) | In 1 condition |
| NEUROD1neuronal differentiation 1 | Sometimes (5–29%) | In 1 condition |
| PAX4paired box 4 | Sometimes (5–29%) | In 1 condition |
| PDX1pancreatic and duodenal homeobox 1 | Sometimes (5–29%) | In 1 condition |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Sometimes (5–29%) | In 1 condition |
| SUFUSUFU negative regulator of hedgehog signaling | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| ABCC9ATP binding cassette subfamily C member 9 | Not recorded | In 1 condition |
| PIGLphosphatidylinositol glycan anchor biosynthesis class L | Not recorded | In 1 condition |
| PIGNphosphatidylinositol glycan anchor biosynthesis class N | Not recorded | In 1 condition |
| PIGTphosphatidylinositol glycan anchor biosynthesis class T | Not recorded | In 1 condition |
| TMCO1transmembrane and coiled-coil domains 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks