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Gene

VPS51

VPS51 subunit of GARP complex

Summary

Cytogenetic location
11q13.1
Coordinates
Chromosome 11: 65,096,214–65,111,862 (GRCh38)
Exons
10 exons across 15.6 kb
Protein
782 amino acids
Also known as
ANG2, ANG3, FFR
Previous symbols
C11orf3, C11orf2
MANE Select transcript
ENST00000279281.8NM_013265.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads VPS51 yet. The test sequences your whole genome, so your data includes it all the same.

How VPS51 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where VPS51 sits. VPS51 and 42 genes near it on chromosome 11, from 64,604,038 to 65,604,037.Chromosome 1111q13.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2564.8 Mb65 Mb65.2 Mb65.4 Mb65.6 MbNRXN2: 64,606,174–64,723,202, reverse strandNRXN2RASGRP2: 64,726,905–64,745,456, reverse strandRASGRP2PYGM: 64,746,389–64,759,990, reverse strandPYGMSF1: 64,764,605–64,778,802, reverse strandSF1MAP4K2: 64,784,918–64,803,245, reverse strandMAP4K2MEN1: 64,803,500–64,811,294, reverse strandMEN1CDC42BPG: 64,823,051–64,844,735, reverse strandCDC42BPGEHD1: 64,851,642–64,888,372, reverse strandEHD1ATG2A: 64,894,531–64,917,249, reverse strandATG2APPP2R5B: 64,917,553–64,934,480, forward strandPPP2R5BGPHA2: 64,934,471–64,935,894, reverse strandGPHA2MAJIN: 64,937,517–64,972,113, reverse strandMAJINBATF2: 64,987,945–64,997,018, reverse strandARL2: 65,013,735–65,024,328, forward strandARL2ARL2-SNX15: 65,014,182–65,040,570, forward strandSNX15: 65,027,404–65,040,578, forward strandSNX15SAC3D1: 65,040,897–65,047,320, forward strandSAC3D1NAALADL1: 65,044,818–65,058,558, reverse strandCDCA5: 65,066,299–65,084,164, reverse strandZFPL1: 65,084,210–65,088,409, forward strandCATSPERH: 65,084,974–65,089,375, reverse strandCATSPERHVPS51: 65,096,214–65,111,862, forward strandVPS51TM7SF2: 65,111,845–65,116,677, forward strandTM7SF2ZNHIT2: 65,116,403–65,117,701, reverse strandZNHIT2FAU: 65,120,182–65,122,221, reverse strandSYVN1: 65,121,780–65,146,912, reverse strandMRPL49: 65,122,183–65,127,371, forward strandSPDYC: 65,166,137–65,173,380, forward strandSPDYCCAPN1: 65,180,566–65,212,006, forward strandCAPN1POLA2: 65,261,835–65,305,959, forward strandPOLA2: 65,261,928–65,326,543, forward strandCDC42EP2: 65,298,955–65,322,662, forward strandCDC42EP2DPF2: 65,333,792–65,354,262, forward strandDPF2TIGD3: 65,354,746–65,357,613, forward strandTIGD3SLC25A45: 65,375,186–65,384,550, reverse strandSLC25A45FRMD8: 65,386,592–65,413,526, forward strandFRMD8SCYL1: 65,525,044–65,538,711, forward strandSCYL1LTBP3: 65,538,556–65,558,930, reverse strandLTBP3ZNRD2: 65,570,459–65,574,203, forward strandZNRD2FAM89B: 65,572,349–65,574,199, forward strandFAM89BEHBP1L1: 65,575,943–65,594,089, forward strandKCNK7: 65,592,836–65,595,996, reverse strandMAP3K11: 65,597,149–65,615,382, reverse strandDiagram of VPS51: 10 exons on the forward strand of chromosome 11Exon 3: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 1: 65,096,214–65,096,478, 265 basesExon 2: 65,096,998–65,097,127, 130 basesExon 3: 65,107,581–65,107,727, 147 basesExon 4: 65,107,803–65,108,022, 220 basesExon 5: 65,108,197–65,108,914, 718 basesExon 6: 65,109,280–65,109,495, 216 basesExon 7: 65,109,705–65,109,923, 219 basesExon 8: 65,110,482–65,110,603, 122 basesExon 9: 65,110,694–65,110,781, 88 basesExon 10: 65,111,327–65,111,862, 536 bases12468105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 15.6 kb; 2,349 of those bases code for the protein.

How a genome test reads VPS51

2

positions in VPS51 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 15.6 kb of VPS51, introns included, not only the 2.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). VPS51 gene: VPS51 subunit of GARP complex. Retrieved 16 October 2026, from https://dantelabs.com/genes/vps51

Vancouver

Dante Labs. VPS51 gene: VPS51 subunit of GARP complex [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/vps51

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