Trait
Dysesthesia
Painful sensations elicited by a nonpainful cutaneous stimulus such as a light touch or gentle stroking over affected areas of the body. Sometimes referred to as hyperpathia or hyperalgesia. Often perceived as an intense burning, dyesthesias may outlast the stimulus by several seconds.
Summary
- Also called
- Dysaesthesia, Hyperalgesia, Hyperpathia
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
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Get my Genome Test23 genes linked to Dysesthesia
Changes in these genes cause rare conditions in which Dysesthesia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CST3cystatin C | Always | In 1 condition |
| FDXRferredoxin reductase | Always | In 1 condition |
| SCN10Asodium voltage-gated channel alpha subunit 10 | Always | In 2 conditions |
| CHST14carbohydrate sulfotransferase 14 | Very often (80–99%) | In 2 conditions |
| DSEdermatan sulfate epimerase | Very often (80–99%) | In 1 condition |
| NLRP3NLR family pyrin domain containing 3 | Very often (80–99%) | In 1 condition |
| PRNPprion protein (Kanno blood group) | Very often (80–99%) | In 1 condition |
| DKK1dickkopf Wnt signaling pathway inhibitor 1 | Often (30–79%) | In 1 condition |
| FMR1fragile X messenger ribonucleoprotein 1 | Often (30–79%) | In 1 condition |
| PMP22peripheral myelin protein 22 | Often (30–79%) | In 1 condition |
| RNF170ring finger protein 170 | Often (30–79%) | In 1 condition |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Often (30–79%) | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Sometimes (5–29%) | In 1 condition |
| ALDH4A1aldehyde dehydrogenase 4 family member A1 | Sometimes (5–29%) | In 1 condition |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Sometimes (5–29%) | In 1 condition |
| GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A | Sometimes (5–29%) | In 1 condition |
| PEX16peroxisomal biogenesis factor 16 | Sometimes (5–29%) | In 1 condition |
| SCN11Asodium voltage-gated channel alpha subunit 11 | Sometimes (5–29%) | In 1 condition |
| SCN9Asodium voltage-gated channel alpha subunit 9 | Sometimes (5–29%) | In 1 condition |
| SPTLC2serine palmitoyltransferase long chain base subunit 2 | Sometimes (5–29%) | In 1 condition |
| SRPX2sushi repeat containing protein X-linked 2 | Sometimes (5–29%) | In 1 condition |
| ZFTAzinc finger translocation associated | Sometimes (5–29%) | In 1 condition |
| NKX6-2NK6 homeobox 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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