Trait
Wedge-shaped vertebrae
Clinical name: Vertebral wedging
An abnormal shape of the vertebral bodies whereby the vertebral bodies are thick on one side and taper to a thin edge at the other.
Summary
- Also called
- anterior wedging, Wedged vertebrae
- Body system
- Abnormality of the musculoskeletal system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Wedge-shaped vertebrae, and the rest of your genome, with one test.
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Get my Genome Test15 genes linked to Wedge-shaped vertebrae
Changes in these genes cause rare conditions in which Wedge-shaped vertebrae is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CANT1calcium activated nucleotidase 1 | Always | In 1 condition |
| FKBP10FKBP prolyl isomerase 10 | Always | In 2 conditions |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Always | In 1 condition |
| SLC13A1solute carrier family 13 member 1 | Always | In 1 condition |
| CCN6cellular communication network factor 6 | Often (30–79%) | In 1 condition |
| COL2A1collagen type II alpha 1 chain | Often (30–79%) | In 3 conditions |
| CUL7cullin 7 | Often (30–79%) | In 1 condition |
| IFT43intraflagellar transport 43 | Often (30–79%) | In 1 condition |
| NPR2natriuretic peptide receptor 2 | Often (30–79%) | In 1 condition |
| PTCH1patched 1 | Often (30–79%) | In 2 conditions |
| PTCH2patched 2 | Often (30–79%) | In 1 condition |
| SUFUSUFU negative regulator of hedgehog signaling | Often (30–79%) | In 1 condition |
| FN1fibronectin 1 | Sometimes (5–29%) | In 1 condition |
| IFITM5interferon induced transmembrane protein 5 | Sometimes (5–29%) | In 1 condition |
| TRPV4transient receptor potential cation channel subfamily V member 4 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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