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Gene

PURA

purine rich element binding protein A

Summary

Cytogenetic location
5q31.3
Coordinates
Chromosome 5: 140,114,109–140,125,619 (GRCh38)
Exons
1 exon across 11.5 kb
Protein
322 amino acids
Also known as
PURALPHA, PUR1, PUR-ALPHA
MANE Select transcript
ENST00000331327.5NM_005859.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PURA yet. The test sequences your whole genome, so your data includes it all the same.

How PURA is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 5, with a bracket where PURA sits. PURA and 16 genes near it on chromosome 5, from 139,619,864 to 140,619,863.Chromosome 55q31.3p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.3139.8 Mb140 Mb140.2 Mb140.4 Mb140.6 MbUBE2D2: 139,526,431–139,633,291, forward strandUBE2D2CXXC5: 139,646,375–139,683,882, forward strandCXXC5PSD2: 139,795,606–139,844,470, forward strandPSD2NRG2: 139,846,779–140,043,328, reverse strandNRG2PURA: 140,114,109–140,125,619, forward strandPURAIGIP: 140,125,937–140,129,392, forward strandIGIPCYSTM1: 140,174,924–140,282,212, forward strandCYSTM1PFDN1: 140,234,986–140,303,119, reverse strandPFDN1HBEGF: 140,332,843–140,346,614, reverse strandHBEGFSLC4A9: 140,360,188–140,375,324, forward strandSLC4A9ANKHD1: 140,401,660–140,541,168, forward strandANKHD1ANKHD1-EIF4EBP3: 140,401,908–140,549,569, forward strandANKHD1-EIF4EBP3SRA1: 140,536,450–140,557,920, reverse strandSRA1EIF4EBP3: 140,547,616–140,551,708, forward strandEIF4EBP3APBB3: 140,558,268–140,564,781, reverse strandSLC35A4: 140,564,440–140,569,215, forward strandSURMIR: 140,564,440–140,569,215, forward strandDiagram of PURA: one exon on the forward strand of chromosome 5Exon 1: 114 known disease-causing sitesExon 1: 140,114,109–140,125,619, 11,511 bases15′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 11.5 kb of the gene's 11.5 kb; 969 of those bases code for the protein.

How a genome test reads PURA

115

positions in PURA where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 11.5 kb of PURA, introns included, not only the 11.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PURA gene: purine rich element binding protein A. Retrieved 17 October 2026, from https://dantelabs.com/genes/pura

Vancouver

Dante Labs. PURA gene: purine rich element binding protein A [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pura

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