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Gene

NOS1AP

nitric oxide synthase 1 adaptor protein

Summary

Cytogenetic location
1q23.3
Coordinates
Chromosome 1: 162,069,691–162,370,475 (GRCh38)
Exons
10 exons across 300.8 kb
Protein
506 amino acids
Also known as
KIAA0464, CAPON
MANE Select transcript
ENST00000361897.10NM_014697.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Nephrotic Syndrome

    • Nephrosis

      Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.

      • 1 GenCC submitter rates it definitive or strong

How NOS1AP is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where NOS1AP sits. NOS1AP and 11 genes near it on chromosome 1, from 161,720,083 to 162,720,082.Chromosome 11q23.3p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44161.8 Mb162 Mb162.2 Mb162.4 Mb162.6 MbFCRLB: 161,721,544–161,731,801, forward strandFCRLBDUSP12: 161,749,758–161,757,238, forward strandDUSP12ATF6: 161,766,243–161,977,574, forward strandATF6OLFML2B: 161,983,191–162,024,389, reverse strandOLFML2BNOS1AP: 162,069,691–162,370,475, forward strandNOS1AP: 162,365,407–162,383,531, forward strandSPATA46: 162,373,203–162,376,874, reverse strandSPATA46C1orf226: 162,378,841–162,386,812, forward strandC1orf226SH2D1B: 162,395,164–162,412,138, reverse strandUHMK1: 162,497,251–162,529,631, forward strandUHMK1UAP1: 162,561,476–162,616,939, forward strandUAP1DDR2: 162,630,857–162,787,405, forward strandDDR2Diagram of NOS1AP: 10 exons on the forward strand of chromosome 1Exon 1: 162,069,691–162,070,282, 592 basesExon 2: 162,154,405–162,154,476, 72 basesExon 3: 162,287,344–162,287,436, 93 basesExon 4: 162,300,633–162,300,706, 74 basesExon 5: 162,333,017–162,333,125, 109 basesExon 6: 162,343,835–162,343,976, 142 basesExon 7: 162,355,187–162,355,353, 167 basesExon 8: 162,356,960–162,357,136, 177 basesExon 9: 162,365,404–162,365,569, 166 basesExon 10: 162,367,052–162,370,475, 3,424 bases12468105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5 kb of the gene's 300.8 kb; 1,521 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NOS1AP gene: nitric oxide synthase 1 adaptor protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/nos1ap

Vancouver

Dante Labs. NOS1AP gene: nitric oxide synthase 1 adaptor protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/nos1ap

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