Trait
Decreased protein levels in blood
Clinical name: Hypoproteinemia
A decreased concentration of protein in the blood.
Summary
- Body system
- Laboratory abnormality
Reference genomeGRCh38hg38
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Get my Genome Test18 genes linked to Decreased protein levels in blood
Changes in these genes cause rare conditions in which Decreased protein levels in blood is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| B2Mbeta-2-microglobulin | Always | In 1 condition |
| NOS1APnitric oxide synthase 1 adaptor protein | Always | In 1 condition |
| NPHS1NPHS1 adhesion molecule, nephrin | Always | In 1 condition |
| ALBalbumin | Often (30–79%) | In 1 condition |
| RBCK1RANBP2-type and C3HC4-type zinc finger containing 1 | Often (30–79%) | In 1 condition |
| SLC25A13solute carrier family 25 member 13 | Often (30–79%) | In 1 condition |
| UBR1ubiquitin protein ligase E3 component n-recognin 1 | Often (30–79%) | In 1 condition |
| DPAGT1dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 | Sometimes (5–29%) | In 1 condition |
| FOCADfocadhesin | Sometimes (5–29%) | In 1 condition |
| LYSTlysosomal trafficking regulator | Sometimes (5–29%) | In 1 condition |
| ACADVLacyl-CoA dehydrogenase very long chain | Rarely (1–4%) | In 1 condition |
| CD55CD55 molecule (Cromer blood group) | Not recorded | In 1 condition |
| DCLRE1CDNA cross-link repair 1C | Not recorded | In 1 condition |
| LAMB2laminin subunit beta 2 | Not recorded | In 1 condition |
| PRF1perforin 1 | Not recorded | In 1 condition |
| RAG1recombination activating 1 | Not recorded | In 1 condition |
| RAG2recombination activating 2 | Not recorded | In 1 condition |
| TMPRSS15transmembrane serine protease 15 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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