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Gene

NEUROD2

neuronal differentiation 2

Summary

Cytogenetic location
17q12
Coordinates
Chromosome 17: 39,603,768–39,607,920 (GRCh38)
Exons
2 exons across 4.2 kb
Protein
382 amino acids
Also known as
NDRF, bHLHa1
MANE Select transcript
ENST00000302584.5NM_006160.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    • Epilepsy (Full Panel)

      • Epilepsy

        One of 171 genes linked to it

        A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions.

        • 2 GenCC submitters rate it definitive or strong

    How NEUROD2 is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Known disease-causing sites
    Chromosome 17, with a bracket where NEUROD2 sits. NEUROD2 and 27 genes near it on chromosome 17, from 39,105,844 to 40,105,843.Chromosome 1717q12p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.339.2 Mb39.4 Mb39.6 Mb39.8 Mb40 MbPLXDC1: 39,063,313–39,154,394, reverse strandPLXDC1ARL5C: 39,156,894–39,167,484, reverse strandARL5CCACNB1: 39,173,453–39,197,877, reverse strandCACNB1RPL19: 39,200,282–39,204,840, forward strandRPL19STAC2: 39,210,540–39,225,945, reverse strandSTAC2FBXL20: 39,252,663–39,402,523, reverse strandFBXL20MED1: 39,404,253–39,451,306, reverse strandMED1CDK12: 39,461,437–39,567,559, forward strandCDK12NEUROD2: 39,603,768–39,607,920, reverse strandNEUROD2PPP1R1B: 39,626,740–39,636,626, forward strandPPP1R1BSTARD3: 39,637,058–39,664,201, forward strandSTARD3TCAP: 39,664,990–39,666,554, forward strandTCAPPNMT: 39,667,981–39,670,484, forward strandPNMTPGAP3: 39,671,120–39,696,797, reverse strandERBB2: 39,687,914–39,730,426, forward strandERBB2MIEN1: 39,728,496–39,730,555, reverse strandMIEN1GRB7: 39,737,490–39,747,292, forward strandGRB7IKZF3: 39,757,715–39,864,368, reverse strandIKZF3ZPBP2: 39,868,202–39,877,896, forward strandZPBP2GSDMB: 39,904,595–39,919,854, reverse strandGSDMBORMDL3: 39,919,927–39,982,186, reverse strandORMDL3LRRC3C: 39,927,725–39,946,538, forward strandLRRC3CGSDMA: 39,953,263–39,977,875, forward strandGSDMAPSMD3: 39,980,800–39,997,960, forward strandPSMD3CSF3: 40,015,361–40,017,816, forward strandCSF3MED24: 40,019,097–40,061,215, reverse strandMED24THRA: 40,058,290–40,093,867, forward strandTHRANR1D1: 40,092,793–40,100,630, reverse strandNR1D1Diagram of NEUROD2: 2 exons on the reverse strand of chromosome 17Exon 2: 4 known disease-causing sitesExon 2: 39,603,768–39,606,604, 2,837 basesExon 1: 39,607,728–39,607,920, 193 bases215′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 3 kb of the gene's 4.2 kb; 1,149 of those bases code for the protein.

    How a genome test reads NEUROD2

    4

    positions in NEUROD2 where ClinVar classes a change as pathogenic or likely pathogenic

    None of them falls in a region short reads find hard.

    A whole genome covers all 4.2 kb of NEUROD2, introns included, not only the 3 kb of exons.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). NEUROD2 gene: neuronal differentiation 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/neurod2

    Vancouver

    Dante Labs. NEUROD2 gene: neuronal differentiation 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/neurod2

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