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Trait
One sided cleft palate
Clinical name: Unilateral cleft palate
Summary
- Also called
- Unilateral palatoschisis
- Body system
- Abnormality of head or neck
One sided cleft palateHP:0100334
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Read the genes linked to One sided cleft palate, and the rest of your genome, with one test.
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Get my Genome Test25 genes linked to One sided cleft palate
Changes in these genes cause rare conditions in which One sided cleft palate is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AMOTL1angiomotin like 1 | Always | In 1 condition |
| MED16mediator complex subunit 16 | Always | In 1 condition |
| SUMO1small ubiquitin like modifier 1 | Always | In 1 condition |
| TP63tumor protein p63 | Always | In 2 conditions |
| CDH11cadherin 11 | Very often (80–99%) | In 1 condition |
| ARHGAP29Rho GTPase activating protein 29 | Often (30–79%) | In 1 condition |
| ARHGEF38Rho guanine nucleotide exchange factor 38 | Often (30–79%) | In 1 condition |
| BMP4bone morphogenetic protein 4 | Often (30–79%) | In 1 condition |
| CDH1cadherin 1 | Often (30–79%) | In 1 condition |
| COBLL1cordon-bleu WH2 repeat protein like 1 | Often (30–79%) | In 1 condition |
| DLG1discs large MAGUK scaffold protein 1 | Often (30–79%) | In 1 condition |
| DLX4distal-less homeobox 4 | Often (30–79%) | In 1 condition |
| GDF11growth differentiation factor 11 | Often (30–79%) | In 1 condition |
| HYAL2hyaluronidase 2 | Often (30–79%) | In 1 condition |
| IRF6interferon regulatory factor 6 | Often (30–79%) | In 1 condition |
| KAT5lysine acetyltransferase 5 | Often (30–79%) | In 1 condition |
| MSX1msh homeobox 1 | Often (30–79%) | In 1 condition |
| NECTIN1nectin cell adhesion molecule 1 | Often (30–79%) | In 1 condition |
| PDGFRAplatelet derived growth factor receptor alpha | Often (30–79%) | In 1 condition |
| RIC1RIC1 partner of RAB6A GEF complex | Often (30–79%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Sometimes (5–29%) | In 1 condition |
| DHRS3dehydrogenase/reductase 3 | Sometimes (5–29%) | In 1 condition |
| EXOC3L2exocyst complex component 3 like 2 | Sometimes (5–29%) | In 1 condition |
| MED12mediator complex subunit 12 | Sometimes (5–29%) | In 1 condition |
| PTCH1patched 1 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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