AtlasTrait
Wide rib cage
Clinical name: Enlarged thorax
Summary
- Also called
- Wide thorax
- Body system
- Abnormality of the musculoskeletal system
AtlasThis page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/traits/enlarged-thorax.json"
page <- fromJSON(url)
page$trait$nameRead the genes linked to Wide rib cage, and the rest of your genome, with one test.
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Get my Genome Test18 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Noonan SyndromeReads 17 of these genesBRAFKRASMAP2K1MAP2K2CBLLZTR1About this report →
- Hypertrophic CardiomyopathyReads 16 of these genesBRAFKRASMAP2K1MAP2K2LZTR1MRASAbout this report →
- Dias-Logan SyndromeReads 1 of these genesBCL11AAbout this report →
- Mucopolysaccharidosis Type VII (Sly Syndrome)Reads 1 of these genesGUSBAbout this report →
Show 14 more reports
- Hereditary Gingival FibromatosisReads 1 of these genesSOS1About this report →
- NeurofibromatosisReads 1 of these genesLZTR1About this report →
- Autoimmune Lymphoproliferative Syndrome (ALPS)Reads 1 of these genesKRASAbout this report →
- Marfan Like SyndromesReads 1 of these genesFBN1About this report →
- Aortic AneurysmReads 1 of these genesFBN1About this report →
- Inherited Congenital Heart DefectsReads 1 of these genesGATA4About this report →
- 46,XY Differences of Sex Development and Gonadal DysgenesisReads 1 of these genesGATA4About this report →
- Neonatal Diabetes MellitusReads 1 of these genesGATA4About this report →
- Autoimmune DiseaseReads 1 of these genesKRASAbout this report →
- Diabetes MellitusReads 1 of these genesGATA4About this report →
- Osteogenesis ImperfectaReads 1 of these genesBMP1About this report →
- Dilated CardiomyopathyReads 1 of these genesRAF1About this report →
- Other Inborn Errors of ImmunityReads 2 of these genesKRASRELAbout this report →
- Lysosomal Storage DiseaseReads 1 of these genesGUSBAbout this report →
Read the genes linked to Wide rib cage, and the rest of your genome, with one test.
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Get my Genome Test30 genes linked to Wide rib cage
Changes in these genes cause rare conditions in which Wide rib cage is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Always | In 2 conditions |
| KRASKRas proto-oncogene, GTPase | Always | In 2 conditions |
| MAP2K1mitogen-activated protein kinase kinase 1 | Always | In 1 condition |
| MAP2K2mitogen-activated protein kinase kinase 2 | Always | In 1 condition |
| BMPERBMP binding endothelial regulator | Very often (80–99%) | In 1 condition |
| CBLCbl proto-oncogene | Very often (80–99%) | In 1 condition |
| FBN1fibrillin 1 | Very often (80–99%) | In 1 condition |
| LZTR1leucine zipper like post translational regulator 1 | Very often (80–99%) | In 1 condition |
| MRASmuscle RAS oncogene homolog | Very often (80–99%) | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Very often (80–99%) | In 1 condition |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Very often (80–99%) | In 1 condition |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Very often (80–99%) | In 1 condition |
| RASA2RAS p21 protein activator 2 | Very often (80–99%) | In 1 condition |
| RIT1Ras like without CAAX 1 | Very often (80–99%) | In 1 condition |
| RRASRAS related | Very often (80–99%) | In 1 condition |
| RRAS2RAS related 2 | Very often (80–99%) | In 1 condition |
| SOS1SOS Ras/Rac guanine nucleotide exchange factor 1 | Very often (80–99%) | In 1 condition |
| SOS2SOS Ras/Rho guanine nucleotide exchange factor 2 | Very often (80–99%) | In 1 condition |
| SPRED2sprouty related EVH1 domain containing 2 | Very often (80–99%) | In 1 condition |
| BMP1bone morphogenetic protein 1 | Often (30–79%) | In 1 condition |
| CCDC8coiled-coil domain containing 8 subunit of 3M complex | Often (30–79%) | In 1 condition |
| CUL7cullin 7 | Often (30–79%) | In 1 condition |
| GATA4GATA binding protein 4 | Often (30–79%) | In 1 condition |
| GPKOWG-patch domain and KOW motifs | Often (30–79%) | In 1 condition |
| OBSL1obscurin like cytoskeletal adaptor 1 | Often (30–79%) | In 1 condition |
| BCL11ABCL11 transcription factor A | Sometimes (5–29%) | In 1 condition |
| GUSBglucuronidase beta | Sometimes (5–29%) | In 1 condition |
| MAPK1mitogen-activated protein kinase 1 | Sometimes (5–29%) | In 1 condition |
| RELREL proto-oncogene, NF-kB subunit | Sometimes (5–29%) | In 1 condition |
| XPO1exportin 1 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.19-9814e911.
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