Trait

Dimple chin

A persistent midline depression of the skin over the fat pad of the chin.

Also called: Chin butt, Chin dent, Chin dimple, Chin dimples, Chin skin dimple, Indentation of chin, Gelasin of chin
Body system: Abnormality of head or neck

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/dimple-chin.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

Read the genes linked to Dimple chin, and the rest of your genome, with one test.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test

20 genes linked to Dimple chin

Changes in these genes cause rare conditions in which Dimple chin is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
KDM6Alysine demethylase 6A	Always	In 1 condition
KMT2Dlysine methyltransferase 2D	Always	In 1 condition
MED16mediator complex subunit 16	Always	In 1 condition
PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Always	In 1 condition
MYH3myosin heavy chain 3	Very often (80–99%)	In 2 conditions
NALCNsodium leak channel, non-selective	Very often (80–99%)	In 1 condition
PIEZO2piezo type mechanosensitive ion channel component 2	Very often (80–99%)	In 1 condition
TWIST2twist family bHLH transcription factor 2	Very often (80–99%)	In 1 condition
CASP2caspase 2	Often (30–79%)	In 1 condition
CHD7chromodomain helicase DNA binding protein 7	Often (30–79%)	In 1 condition
KCNJ6potassium inwardly rectifying channel subfamily J member 6	Often (30–79%)	In 1 condition
RUNX2RUNX family transcription factor 2	Often (30–79%)	In 1 condition
SEMA3Esemaphorin 3E	Often (30–79%)	In 1 condition
SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2	Often (30–79%)	In 1 condition
TFAP2Atranscription factor AP-2 alpha	Often (30–79%)	In 1 condition
SPECC1Lsperm antigen with calponin homology and coiled-coil domains 1 like	Sometimes (5–29%)	In 1 condition
TBX22T-box transcription factor 22	Sometimes (5–29%)	In 1 condition
CTU2cytosolic thiouridylase subunit 2	Not recorded	In 1 condition
EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit	Not recorded	In 1 condition
PIK3R1phosphoinositide-3-kinase regulatory subunit 1	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormality of the chin

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.17-8666dff2.

One test. A lifetime of answers.