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Gene

TLCD3B

TLC domain containing 3B

Summary

Cytogenetic location
16p11.2
Coordinates
Chromosome 16: 30,024,427–30,031,271 (GRCh38)
Exons
5 exons across 6.8 kb
Protein
274 amino acids
Also known as
DKFZP434I2117
Previous symbols
FAM57B
MANE Select transcript
ENST00000380495.9NM_031478.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TLCD3B yet. The test sequences your whole genome, so your data includes it all the same.

How TLCD3B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 16, with a bracket where TLCD3B sits. TLCD3B and 44 genes near it on chromosome 16, from 29,527,849 to 30,527,848.Chromosome 1616p11.2p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.329.6 Mb29.8 Mb30 Mb30.2 Mb30.4 MbQPRT: 29,662,957–29,698,704, forward strandQPRTSPN: 29,662,957–29,670,876, forward strandSPNC16orf54: 29,742,463–29,746,079, reverse strandC16orf54ZG16: 29,760,591–29,783,885, forward strandZG16KIF22: 29,790,137–29,805,388, forward strandMAZ: 29,805,637–29,811,176, forward strandPRRT2: 29,811,382–29,815,892, forward strand: 29,812,261–29,820,092, forward strandPAGR1: 29,816,086–29,822,489, forward strandPAGR1: 29,817,239–29,830,627, forward strandMVP: 29,820,394–29,848,039, forward strandMVPCDIPT: 29,857,474–29,863,414, reverse strandCDIPTSEZ6L2: 29,871,159–29,899,582, reverse strandSEZ6L2ASPHD1: 29,900,363–29,919,864, forward strandASPHD1KCTD13: 29,903,877–29,926,236, reverse strandKCTD13TMEM219: 29,940,885–29,973,052, forward strandTMEM219TAOK2: 29,973,675–29,992,262, forward strandHIRIP3: 29,992,314–29,996,126, reverse strandINO80E: 29,994,983–30,005,794, forward strandINO80EDOC2A: 30,005,507–30,023,270, reverse strandDOC2AFIMP1: 30,023,198–30,027,736, forward strandFIMP1TLCD3B: 30,024,427–30,031,271, reverse strandTLCD3B: 30,053,101–30,071,526, forward strandALDOA: 30,064,164–30,070,457, forward strandALDOAPPP4C: 30,075,967–30,085,391, forward strandPPP4CTBX6: 30,085,793–30,091,933, reverse strandTBX6YPEL3: 30,092,314–30,096,915, reverse strandGDPD3: 30,104,810–30,114,034, reverse strandMAPK3: 30,114,104–30,123,506, reverse strandCORO1A: 30,182,798–30,189,085, forward strandCORO1ABOLA2B: 30,192,928–30,194,306, reverse strandBOLA2BSLX1A: 30,193,875–30,197,566, forward strandSLX1ASULT1A3: 30,198,059–30,204,324, forward strandSULT1A3NPIPB13: 30,222,893–30,255,268, reverse strandCD2BP2: 30,341,365–30,355,851, reverse strandCD2BP2TBC1D10B: 30,357,102–30,370,529, reverse strandTBC1D10BMYL11: 30,370,332–30,377,991, forward strandMYL11ZNF48: 30,378,106–30,400,108, forward strandSEPTIN1: 30,378,135–30,395,991, reverse strandSEPTIN1ZNF771: 30,407,143–30,431,108, forward strandDCTPP1: 30,413,033–30,430,162, reverse strandSEPHS2: 30,443,631–30,445,874, reverse strandSEPHS2ITGAL: 30,472,658–30,523,567, forward strandITGALZNF768: 30,524,001–30,527,328, reverse strandZNF768: 30,525,923–30,534,852, reverse strandDiagram of TLCD3B: 5 exons on the reverse strand of chromosome 16Exon 2: 1 known disease-causing siteExon 5: 30,024,427–30,025,467, 1,041 basesExon 4: 30,025,726–30,025,821, 96 basesExon 3: 30,026,609–30,026,843, 235 basesExon 2: 30,029,432–30,029,515, 84 basesExon 1: 30,030,403–30,031,271, 869 bases543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.3 kb of the gene's 6.8 kb; 825 of those bases code for the protein.

How a genome test reads TLCD3B

1

position in TLCD3B where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 6.8 kb of TLCD3B, introns included, not only the 2.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TLCD3B gene: TLC domain containing 3B. Retrieved 17 October 2026, from https://dantelabs.com/genes/tlcd3b

Vancouver

Dante Labs. TLCD3B gene: TLC domain containing 3B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tlcd3b

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