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Gene

POC1B

POC1 centriolar protein B

Summary

Cytogenetic location
12q21.33
Coordinates
Chromosome 12: 89,419,718–89,526,047 (GRCh38)
Exons
12 exons across 106.3 kb
Protein
478 amino acids
Also known as
TUWD12, FLJ14923
Previous symbols
WDR51B
MANE Select transcript
ENST00000313546.8NM_172240.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads POC1B yet. The test sequences your whole genome, so your data includes it all the same.

How POC1B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 12, with a bracket where POC1B sits. POC1B and 4 genes near it on chromosome 12, from 88,972,883 to 89,972,882.Chromosome 1212q21.33p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3389 Mb89.2 Mb89.4 Mb89.6 Mb89.8 MbDUSP6: 89,347,235–89,352,507, reverse strandDUSP6POC1B: 89,419,718–89,526,047, reverse strandPOC1BPOC1B-GALNT4: 89,519,408–89,526,262, reverse strandPOC1B-GALNT4GALNT4: 89,519,412–89,524,796, reverse strandGALNT4ATP2B1: 89,588,049–89,709,642, reverse strandATP2B1Diagram of POC1B: 12 exons on the reverse strand of chromosome 12Exon 10: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 4: 3 known disease-causing sitesExon 3: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 12: 89,419,718–89,421,257, 1,540 basesExon 11: 89,425,161–89,425,379, 219 basesExon 10: 89,459,638–89,459,718, 81 basesExon 9: 89,466,770–89,466,922, 153 basesExon 8: 89,467,617–89,467,685, 69 basesExon 7: 89,470,361–89,470,494, 134 basesExon 6: 89,471,614–89,471,729, 116 basesExon 5: 89,472,168–89,472,275, 108 basesExon 4: 89,491,936–89,492,115, 180 basesExon 3: 89,497,171–89,497,342, 172 basesExon 2: 89,525,120–89,525,204, 85 basesExon 1: 89,525,881–89,526,047, 167 bases1210515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3 kb of the gene's 106.3 kb; 1,437 of those bases code for the protein.

How a genome test reads POC1B

15

positions in POC1B where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 106.3 kb of POC1B, introns included, not only the 3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). POC1B gene: POC1 centriolar protein B. Retrieved 17 October 2026, from https://dantelabs.com/genes/poc1b

Vancouver

Dante Labs. POC1B gene: POC1 centriolar protein B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/poc1b

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