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Gene

TELO2

telomere maintenance 2

Summary

Cytogenetic location
16p13.3
Coordinates
Chromosome 16: 1,493,360–1,510,454 (GRCh38)
Exons
21 exons across 17.1 kb
Protein
837 amino acids
Also known as
KIAA0683, hCLK2, TEL2
MANE Select transcript
ENST00000262319.11NM_016111.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TELO2 yet. The test sequences your whole genome, so your data includes it all the same.

How TELO2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 16, with a bracket where TELO2 sits. TELO2 and 43 genes near it on chromosome 16, from 1,001,907 to 2,001,906.Chromosome 1616p13.3p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.31.2 Mb1.4 Mb1.6 Mb1.8 Mb2 MbSSTR5: 1,063,867–1,081,470, forward strandSSTR5C1QTNF8: 1,088,226–1,099,401, reverse strandC1QTNF8CACNA1H: 1,153,099–1,224,169, forward strandCACNA1HTPSG1: 1,221,651–1,225,793, reverse strandTPSG1TPSB2: 1,227,272–1,233,725, reverse strandTPSB2TPSAB1: 1,239,266–1,242,555, forward strandTPSAB1TPSD1: 1,256,059–1,259,008, forward strandTPSD1UBE2I: 1,291,357–1,327,018, forward strandUBE2IBAIAP3: 1,333,638–1,349,439, forward strandBAIAP3TSR3: 1,349,236–1,351,898, reverse strandTSR3GNPTG: 1,351,924–1,365,737, forward strandGNPTGUNKL: 1,363,205–1,414,751, reverse strandUNKLUQCC4: 1,419,752–1,420,756, reverse strandUQCC4PERCC1: 1,431,078–1,434,441, forward strandPERCC1CCDC154: 1,434,383–1,444,556, reverse strandCCDC154CLCN7: 1,444,934–1,475,104, reverse strandCLCN7PTX4: 1,485,886–1,488,981, reverse strandPTX4TELO2: 1,493,360–1,510,454, forward strandTELO2IFT140: 1,510,427–1,612,082, reverse strandIFT140TMEM204: 1,528,674–1,555,580, forward strandTMEM204CRAMP1: 1,612,337–1,677,908, forward strandCRAMP1: 1,632,259–1,686,715, forward strandJPT2: 1,678,256–1,702,859, forward strandJPT2MAPK8IP3: 1,706,166–1,770,374, forward strandMAPK8IP3NME3: 1,770,317–1,771,746, reverse strandNME3MRPS34: 1,771,889–1,773,487, reverse strandMRPS34EME2: 1,772,283–1,781,708, forward strandEME2SPSB3: 1,776,710–1,793,700, reverse strandNUBP2: 1,782,932–1,789,189, forward strandIGFALS: 1,790,227–1,794,971, reverse strandHAGH: 1,795,620–1,827,187, reverse strandFAHD1: 1,826,967–1,842,053, forward strandFAHD1MEIOB: 1,833,986–1,884,294, reverse strandMEIOBHS3ST6: 1,911,475–1,918,415, reverse strandHS3ST6MSRB1: 1,935,685–1,943,270, reverse strandMSRB1RPL3L: 1,943,791–1,957,606, reverse strandRPL3LNDUFB10: 1,959,500–1,962,105, forward strandNDUFB10RPS2: 1,961,987–1,965,510, reverse strandRNF151: 1,966,823–1,968,975, forward strandTBL3: 1,971,972–1,983,056, forward strandNOXO1: 1,978,912–1,984,636, reverse strandGFER: 1,983,699–1,987,749, forward strandSYNGR3: 1,989,637–1,994,275, forward strandZNF598: 1,997,654–2,009,821, reverse strandDiagram of TELO2: 21 exons on the forward strand of chromosome 16Exon 3: 2 known disease-causing sitesExon 5: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 9: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 15: 4 known disease-causing sitesExon 18: 2 known disease-causing sitesExon 20: 1 known disease-causing siteExon 1: 1,493,360–1,493,605, 246 basesExon 2: 1,494,246–1,494,616, 371 basesExon 3: 1,495,346–1,495,623, 278 basesExon 4: 1,497,036–1,497,104, 69 basesExon 5: 1,497,361–1,497,508, 148 basesExon 6: 1,499,231–1,499,333, 103 basesExon 7: 1,500,096–1,500,164, 69 basesExon 8: 1,500,347–1,500,488, 142 basesExon 9: 1,500,563–1,500,699, 137 basesExon 10: 1,501,420–1,501,499, 80 basesExon 11: 1,501,663–1,501,773, 111 basesExon 12: 1,502,047–1,502,135, 89 basesExon 13: 1,502,313–1,502,404, 92 basesExon 14: 1,502,645–1,502,761, 117 basesExon 15: 1,502,931–1,503,002, 72 basesExon 16: 1,505,410–1,505,601, 192 basesExon 17: 1,506,238–1,506,329, 92 basesExon 18: 1,506,952–1,507,051, 100 basesExon 19: 1,507,306–1,507,370, 65 basesExon 20: 1,507,601–1,507,716, 116 basesExon 21: 1,509,830–1,510,454, 625 bases12468101214161820215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.3 kb of the gene's 17.1 kb; 2,514 of those bases code for the protein.

How a genome test reads TELO2

19

positions in TELO2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 17.1 kb of TELO2, introns included, not only the 3.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TELO2 gene: telomere maintenance 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/telo2

Vancouver

Dante Labs. TELO2 gene: telomere maintenance 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/telo2

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