Trait
Double aortic arch
A conenital abnormality of the aortic arch in which the two embryonic aortc arches form a vascular ring that surrounds the trachea or esophagus and then join to form the descending aorta. Double aortic arch can cause symptoms because of compression of the esophagus (dysphagia, cyanosis while eating) or trachea (stridor).
Summary
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
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Get my Genome Test9 genes linked to Double aortic arch
Changes in these genes cause rare conditions in which Double aortic arch is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GBA1glucosylceramidase beta 1 | Often (30–79%) | In 1 condition |
| TELO2telomere maintenance 2 | Often (30–79%) | In 1 condition |
| DGCR2DiGeorge syndrome critical region gene 2 | Sometimes (5–29%) | In 1 condition |
| DGCR6DiGeorge syndrome critical region gene 6 | Sometimes (5–29%) | In 1 condition |
| DGCR8DGCR8 microprocessor complex subunit | Sometimes (5–29%) | In 1 condition |
| ESS2ess-2 spliceosome associated protein | Sometimes (5–29%) | In 1 condition |
| TBX1T-box transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| CIROPciliated left-right organizer metallopeptidase | Rarely (1–4%) | In 1 condition |
| FLT4fms related receptor tyrosine kinase 4 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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