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Gene

RBCK1

RANBP2-type and C3HC4-type zinc finger containing 1

Summary

Cytogenetic location
20p13
Coordinates
Chromosome 20: 408,299–432,139 (GRCh38)
Exons
12 exons across 23.8 kb
Protein
510 amino acids
Also known as
RBCK2, XAP4, RNF54, ZRANB4, UBCE7IP3, HOIL1
Previous symbols
C20orf18
MANE Select transcript
ENST00000356286.10NM_031229.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads RBCK1 yet. The test sequences your whole genome, so your data includes it all the same.

How RBCK1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 20, with a bracket where RBCK1 sits. RBCK1 and 20 genes near it on chromosome 20, from 1 to 920,218.Chromosome 2020p13p13p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12q13.11q13.12q13.13q13.2q13.31q13.32q13.330.2 Mb0.4 Mb0.6 Mb0.8 MbDEFB125: 87,250–97,094, forward strandDEFB125DEFB126: 142,590–145,751, forward strandDEFB126DEFB127: 157,454–159,163, forward strandDEFB127DEFB128: 187,853–189,711, reverse strandDEFB128DEFB129: 227,258–229,886, forward strandDEFB129DEFB132: 257,717–261,096, forward strandDEFB132C20orf96: 270,863–290,778, reverse strandC20orf96ZCCHC3: 297,570–300,321, forward strandZCCHC3SOX12: 325,552–330,224, forward strandSOX12NRSN2: 346,695–359,706, forward strandNRSN2TRIB3: 362,835–398,964, forward strandTRIB3RBCK1: 408,299–432,139, forward strandRBCK1TBC1D20: 423,596–462,566, reverse strandTBC1D20CSNK2A1: 472,498–543,835, reverse strandCSNK2A1TCF15: 603,801–610,316, reverse strandTCF15SRXN1: 646,614–653,404, reverse strandSRXN1: 646,626–675,800, reverse strandSCRT2: 661,596–675,802, reverse strandSCRT2SLC52A3: 758,695–776,015, reverse strandSLC52A3FAM110A: 833,707–857,463, forward strandFAM110AANGPT4: 869,900–916,335, reverse strandANGPT4Diagram of RBCK1: 12 exons on the forward strand of chromosome 20Exon 2: 2 known disease-causing sitesExon 3: 1 known disease-causing siteExon 4: 3 known disease-causing sitesExon 5: 2 known disease-causing sitesExon 6: 9 known disease-causing sitesExon 7: 3 known disease-causing sitesExon 8: 3 known disease-causing sitesExon 9: 9 known disease-causing sitesExon 10: 1 known disease-causing siteExon 11: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 1: 408,299–408,779, 481 basesExon 2: 409,881–410,025, 145 basesExon 3: 417,526–417,619, 94 basesExon 4: 417,732–417,930, 199 basesExon 5: 419,347–419,468, 122 basesExon 6: 419,558–419,731, 174 basesExon 7: 420,871–421,031, 161 basesExon 8: 422,127–422,238, 112 basesExon 9: 427,313–427,492, 180 basesExon 10: 428,491–428,589, 99 basesExon 11: 428,951–429,094, 144 basesExon 12: 430,350–432,139, 1,790 bases1246810125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 23.8 kb; 1,533 of those bases code for the protein.

How a genome test reads RBCK1

39

positions in RBCK1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 23.8 kb of RBCK1, introns included, not only the 3.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RBCK1 gene: RANBP2-type and C3HC4-type zinc finger containing 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/rbck1

Vancouver

Dante Labs. RBCK1 gene: RANBP2-type and C3HC4-type zinc finger containing 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rbck1

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