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Gene

MMP13

matrix metallopeptidase 13

Summary

Cytogenetic location
11q22.2
Coordinates
Chromosome 11: 102,942,995–102,955,732 (GRCh38)
Exons
10 exons across 12.7 kb
Protein
471 amino acids
Also known as
CLG3
MANE Select transcript
ENST00000260302.8NM_002427.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MMP13 yet. The test sequences your whole genome, so your data includes it all the same.

How MMP13 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 11, with a bracket where MMP13 sits. MMP13 and 11 genes near it on chromosome 11, from 102,449,364 to 103,449,363.Chromosome 1111q22.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25102.6 Mb102.8 Mb103 Mb103.2 Mb103.4 MbTMEM123: 102,396,329–102,470,384, reverse strandTMEM123MMP7: 102,520,508–102,530,853, reverse strandMMP7MMP20: 102,576,832–102,625,332, reverse strandMMP20MMP27: 102,691,487–102,705,778, reverse strandMMP27MMP8: 102,711,796–102,727,050, reverse strandMMP8MMP10: 102,770,502–102,780,628, reverse strandMMP10MMP1: 102,789,401–102,798,167, reverse strandMMP1MMP3: 102,835,801–102,843,615, reverse strandMMP3MMP12: 102,862,734–102,874,990, reverse strandMMP12MMP13: 102,942,995–102,955,732, reverse strandMMP13DCUN1D5: 103,050,686–103,092,203, reverse strandDCUN1D5DYNC2H1: 103,109,351–103,479,863, forward strandDYNC2H1Diagram of MMP13: 10 exons on the reverse strand of chromosome 11Exon 4: 1 known disease-causing siteExon 2: 5 known disease-causing sitesExon 10: 102,942,995–102,944,366, 1,372 basesExon 9: 102,945,646–102,945,749, 104 basesExon 8: 102,947,891–102,948,050, 160 basesExon 7: 102,949,025–102,949,158, 134 basesExon 6: 102,950,110–102,950,227, 118 basesExon 5: 102,952,012–102,952,173, 162 basesExon 4: 102,954,156–102,954,281, 126 basesExon 3: 102,954,458–102,954,606, 149 basesExon 2: 102,955,252–102,955,493, 242 basesExon 1: 102,955,586–102,955,732, 147 bases109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 12.7 kb; 1,416 of those bases code for the protein.

How a genome test reads MMP13

6

positions in MMP13 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 12.7 kb of MMP13, introns included, not only the 2.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). MMP13 gene: matrix metallopeptidase 13. Retrieved 17 October 2026, from https://dantelabs.com/genes/mmp13

Vancouver

Dante Labs. MMP13 gene: matrix metallopeptidase 13 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mmp13

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