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Gene

MMP12

matrix metallopeptidase 12

Summary

Cytogenetic location
11q22.2
Coordinates
Chromosome 11: 102,862,736–102,874,982 (GRCh38)
Exons
10 exons across 12.2 kb
Protein
470 amino acids
Also known as
HME
MANE Select transcript
ENST00000571244.3NM_002426.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MMP12 yet. The test sequences your whole genome, so your data includes it all the same.

How MMP12 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where MMP12 sits. MMP12 and 12 genes near it on chromosome 11, from 102,368,859 to 103,368,858.Chromosome 1111q22.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25102.4 Mb102.6 Mb102.8 Mb103 Mb103.2 MbBIRC2: 102,347,208–102,378,680, forward strandBIRC2TMEM123: 102,396,329–102,470,384, reverse strandTMEM123MMP7: 102,520,508–102,530,853, reverse strandMMP7MMP20: 102,576,832–102,625,332, reverse strandMMP20MMP27: 102,691,487–102,705,778, reverse strandMMP27MMP8: 102,711,796–102,727,050, reverse strandMMP8MMP10: 102,770,502–102,780,628, reverse strandMMP10MMP1: 102,789,401–102,798,167, reverse strandMMP1MMP3: 102,835,801–102,843,615, reverse strandMMP3MMP12: 102,862,736–102,874,982, reverse strandMMP12MMP13: 102,942,994–102,955,740, reverse strandMMP13DCUN1D5: 103,050,686–103,092,203, reverse strandDCUN1D5DYNC2H1: 103,109,351–103,479,863, forward strandDYNC2H1Diagram of MMP12: 10 exons on the reverse strand of chromosome 11Exon 10: 102,862,736–102,863,200, 465 basesExon 9: 102,864,146–102,864,252, 107 basesExon 8: 102,865,776–102,865,935, 160 basesExon 7: 102,866,315–102,866,448, 134 basesExon 6: 102,867,270–102,867,393, 124 basesExon 5: 102,867,908–102,868,069, 162 basesExon 4: 102,871,594–102,871,719, 126 basesExon 3: 102,871,804–102,871,952, 149 basesExon 2: 102,872,865–102,873,112, 248 basesExon 1: 102,874,836–102,874,982, 147 bases109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.8 kb of the gene's 12.2 kb; 1,413 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). MMP12 gene: matrix metallopeptidase 12. Retrieved 17 October 2026, from https://dantelabs.com/genes/mmp12

Vancouver

Dante Labs. MMP12 gene: matrix metallopeptidase 12 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mmp12

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