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Gene

DNAH10

dynein axonemal heavy chain 10

Summary

Cytogenetic location
12q24.31
Coordinates
Chromosome 12: 123,762,301–123,935,714 (GRCh38)
Exons
79 exons across 173.4 kb
Protein
4,589 amino acids
Also known as
FLJ43808
MANE Select transcript
ENST00000673944.1NM_001372106.1
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Male Infertility

    • The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

      • ClinGen rates the link moderate
      • 1 GenCC submitter rates it definitive or strong

How DNAH10 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 12, with a bracket where DNAH10 sits. DNAH10 and 15 genes near it on chromosome 12, from 123,349,008 to 124,349,007.Chromosome 1212q24.31p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.33123.4 Mb123.6 Mb123.8 Mb124 Mb124.2 MbSBNO1: 123,289,109–123,365,220, reverse strandSBNO1KMT5A: 123,384,087–123,409,353, forward strandKMT5ARILPL2: 123,409,258–123,436,756, reverse strandRILPL2SNRNP35: 123,458,078–123,473,154, forward strandSNRNP35RILPL1: 123,467,802–123,534,417, reverse strandRILPL1TMED2: 123,584,514–123,598,582, forward strandTMED2DDX55: 123,602,073–123,620,943, forward strandDDX55EIF2B1: 123,620,406–123,633,766, reverse strandEIF2B1GTF2H3: 123,633,739–123,662,604, forward strandGTF2H3TCTN2: 123,671,110–123,708,403, forward strandTCTN2ATP6V0A2: 123,712,334–123,761,760, forward strandATP6V0A2DNAH10: 123,762,301–123,935,714, forward strandDNAH10CCDC92: 123,918,660–123,974,253, reverse strandCCDC92ZNF664: 123,971,745–124,015,445, forward strandZNF664RFLNA: 123,973,241–124,316,024, forward strandRFLNANCOR2: 124,324,407–124,567,647, reverse strandNCOR2Diagram of DNAH10: 79 exons on the forward strand of chromosome 12Exon 6: 1 known disease-causing siteExon 15: 1 known disease-causing siteExon 23: 1 known disease-causing siteExon 25: 1 known disease-causing siteExon 34: 1 known disease-causing siteExon 45: 2 known disease-causing sitesExon 63: 1 known disease-causing siteExon 76: 1 known disease-causing siteExon 1: 123,762,301–123,762,550, 250 basesExon 2: 123,767,606–123,767,689, 84 basesExon 3: 123,771,601–123,771,698, 98 basesExon 4: 123,772,834–123,772,942, 109 basesExon 5: 123,774,149–123,774,264, 116 basesExon 6: 123,781,080–123,781,299, 220 basesExon 7: 123,783,107–123,783,264, 158 basesExon 8: 123,783,947–123,784,177, 231 basesExon 9: 123,785,746–123,785,936, 191 basesExon 10: 123,787,804–123,788,002, 199 basesExon 11: 123,789,927–123,790,121, 195 basesExon 12: 123,793,942–123,794,112, 171 basesExon 13: 123,796,656–123,796,832, 177 basesExon 14: 123,799,246–123,799,371, 126 basesExon 15: 123,800,216–123,800,388, 173 basesExon 16: 123,801,281–123,801,432, 152 basesExon 17: 123,803,661–123,803,825, 165 basesExon 18: 123,804,833–123,805,040, 208 basesExon 19: 123,808,797–123,808,953, 157 basesExon 20: 123,813,164–123,813,640, 477 basesExon 21: 123,813,754–123,813,912, 159 basesExon 22: 123,818,950–123,819,066, 117 basesExon 23: 123,819,148–123,819,250, 103 basesExon 24: 123,820,580–123,820,758, 179 basesExon 25: 123,826,687–123,826,898, 212 basesExon 26: 123,830,546–123,830,699, 154 basesExon 27: 123,833,114–123,833,347, 234 basesExon 28: 123,835,406–123,835,528, 123 basesExon 29: 123,838,456–123,838,689, 234 basesExon 30: 123,841,322–123,841,545, 224 basesExon 31: 123,845,600–123,845,869, 270 basesExon 32: 123,845,971–123,846,154, 184 basesExon 33: 123,847,961–123,848,095, 135 basesExon 34: 123,848,730–123,848,882, 153 basesExon 35: 123,850,888–123,851,076, 189 basesExon 36: 123,853,206–123,853,352, 147 basesExon 37: 123,857,056–123,857,247, 192 basesExon 38: 123,859,150–123,859,268, 119 basesExon 39: 123,861,012–123,861,170, 159 basesExon 40: 123,864,595–123,864,730, 136 basesExon 41: 123,865,951–123,866,073, 123 basesExon 42: 123,867,467–123,867,601, 135 basesExon 43: 123,867,903–123,868,119, 217 basesExon 44: 123,870,366–123,870,485, 120 basesExon 45: 123,871,457–123,871,602, 146 basesExon 46: 123,873,558–123,873,710, 153 basesExon 47: 123,875,231–123,875,491, 261 basesExon 48: 123,877,736–123,877,908, 173 basesExon 49: 123,879,264–123,879,357, 94 basesExon 50: 123,879,634–123,879,801, 168 basesExon 51: 123,881,625–123,881,813, 189 basesExon 52: 123,887,142–123,887,313, 172 basesExon 53: 123,893,233–123,893,436, 204 basesExon 54: 123,894,643–123,894,723, 81 basesExon 55: 123,897,770–123,897,967, 198 basesExon 56: 123,898,653–123,898,814, 162 basesExon 57: 123,902,939–123,903,113, 175 basesExon 58: 123,909,261–123,909,442, 182 basesExon 59: 123,910,536–123,910,672, 137 basesExon 60: 123,913,098–123,913,315, 218 basesExon 61: 123,914,329–123,914,550, 222 basesExon 62: 123,914,852–123,914,999, 148 basesExon 63: 123,916,457–123,916,736, 280 basesExon 64: 123,917,584–123,917,813, 230 basesExon 65: 123,918,676–123,918,949, 274 basesExon 66: 123,923,763–123,923,867, 105 basesExon 67: 123,924,278–123,924,432, 155 basesExon 68: 123,925,050–123,925,204, 155 basesExon 69: 123,926,637–123,926,820, 184 basesExon 70: 123,928,387–123,928,587, 201 basesExon 71: 123,929,275–123,929,484, 210 basesExon 72: 123,929,664–123,929,759, 96 basesExon 73: 123,930,402–123,930,573, 172 basesExon 74: 123,931,341–123,931,472, 132 basesExon 75: 123,931,636–123,931,847, 212 basesExon 76: 123,931,941–123,932,108, 168 basesExon 77: 123,933,331–123,933,511, 181 basesExon 78: 123,934,621–123,934,766, 146 basesExon 79: 123,935,335–123,935,714, 380 bases110203040506070795′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 14 kb of the gene's 173.4 kb; 13,770 of those bases code for the protein.

How a genome test reads DNAH10

10

positions in DNAH10 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 173.4 kb of DNAH10, introns included, not only the 14 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DNAH10 gene: dynein axonemal heavy chain 10. Retrieved 16 October 2026, from https://dantelabs.com/genes/dnah10

Vancouver

Dante Labs. DNAH10 gene: dynein axonemal heavy chain 10 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dnah10

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