Skip to content
Use your HSA or FSA funds

Gene

AURKC

aurora kinase C

Summary

Cytogenetic location
19q13.43
Coordinates
Chromosome 19: 57,231,023–57,235,548 (GRCh38)
Exons
7 exons across 4.5 kb
Protein
309 amino acids
Also known as
AurC, ARK3
Previous symbols
STK13
MANE Select transcript
ENST00000302804.12NM_001015878.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Male Infertility

    • The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

      • ClinGen rates the link definitive
      • 5 GenCC submitters rate it definitive or strong

How AURKC is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 19, with a bracket where AURKC sits. AURKC and 36 genes near it on chromosome 19, from 56,733,286 to 57,733,285.Chromosome 1919q13.43p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4356.8 Mb57 Mb57.2 Mb57.4 Mb57.6 MbZIM2: 56,754,335–56,840,755, reverse strandZIM2PEG3: 56,810,077–56,840,729, reverse strandPEG3USP29: 57,119,138–57,131,926, forward strandUSP29ZIM3: 57,134,096–57,145,202, reverse strandZIM3DUXA: 57,154,021–57,167,485, reverse strandDUXAZNF264: 57,191,465–57,222,846, forward strandZNF264AURKC: 57,231,023–57,235,548, forward strandAURKCZNF805: 57,240,613–57,274,149, forward strandZNF805ZNF460: 57,279,926–57,296,357, forward strandZNF460ZNF543: 57,320,462–57,335,049, forward strandZNF543ZNF304: 57,351,255–57,360,022, forward strandZNF304ZNF547: 57,363,477–57,379,565, forward strandZNF547TRAPPC2B: 57,363,478–57,365,509, forward strandTRAPPC2B: 57,363,566–57,398,584, forward strandZNF548: 57,389,841–57,404,246, forward strand: 57,389,884–57,419,994, forward strand: 57,394,183–57,438,457, forward strandZNF17: 57,410,723–57,422,156, forward strandZNF749: 57,435,263–57,449,309, forward strandZNF749ZNF772: 57,436,886–57,477,571, reverse strandZNF772: 57,437,970–57,477,536, reverse strandVN1R1: 57,454,790–57,457,140, reverse strandVN1R1ZNF419: 57,487,711–57,496,098, forward strand: 57,487,718–57,517,559, forward strandZNF773: 57,499,877–57,519,627, forward strandZNF549: 57,527,316–57,557,542, forward strandZNF549ZNF550: 57,535,257–57,559,870, reverse strandZNF550ZNF416: 57,571,016–57,578,921, reverse strandZNF416ZIK1: 57,578,456–57,595,040, forward strandZIK1ZNF530: 57,599,874–57,612,722, forward strandZNF530ZNF134: 57,614,233–57,624,724, forward strandZNF134ZNF211: 57,630,395–57,644,044, forward strandZNF211ZSCAN4: 57,668,935–57,679,152, forward strandZSCAN4ZNF551: 57,681,969–57,717,397, forward strandZNF551: 57,682,045–57,753,575, forward strandZNF154: 57,696,275–57,709,215, reverse strandZNF154ZNF671: 57,719,751–57,727,648, reverse strandDiagram of AURKC: 7 exons on the forward strand of chromosome 19Exon 2: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 1: 57,231,023–57,231,306, 284 basesExon 2: 57,231,742–57,231,787, 46 basesExon 3: 57,232,033–57,232,224, 192 basesExon 4: 57,232,542–57,232,680, 139 basesExon 5: 57,233,460–57,233,608, 149 basesExon 6: 57,234,884–57,235,058, 175 basesExon 7: 57,235,247–57,235,548, 302 bases12345675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.3 kb of the gene's 4.5 kb; 930 of those bases code for the protein.

How a genome test reads AURKC

3

positions in AURKC where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 4.5 kb of AURKC, introns included, not only the 1.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). AURKC gene: aurora kinase C. Retrieved 16 October 2026, from https://dantelabs.com/genes/aurkc

Vancouver

Dante Labs. AURKC gene: aurora kinase C [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/aurkc

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test