Trait
Subcapsular cataract
A cataract that affects the region of the lens directly beneath the capsule of the lens.
Summary
- Also called
- Subcapsular cataracts, Subcapsular lenticular cataracts, Subcapsular opacities
- Body system
- Abnormality of the eye
Reference genomeGRCh38hg38
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Get my Genome Test16 genes linked to Subcapsular cataract
Changes in these genes cause rare conditions in which Subcapsular cataract is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| NR6A1nuclear receptor subfamily 6 group A member 1 | Always | In 1 condition |
| TMEM216transmembrane protein 216 | Always | In 1 condition |
| CYP1B1cytochrome P450 family 1 subfamily B member 1 | Very often (80–99%) | In 1 condition |
| FOXC1forkhead box C1 | Very often (80–99%) | In 1 condition |
| FOXE3forkhead box E3 | Very often (80–99%) | In 1 condition |
| PAX6paired box 6 | Very often (80–99%) | In 1 condition |
| PITX2paired like homeodomain 2 | Very often (80–99%) | In 1 condition |
| ABHD5abhydrolase domain containing 5, lysophosphatidic acid acyltransferase | Often (30–79%) | In 2 conditions |
| OATornithine aminotransferase | Often (30–79%) | In 1 condition |
| PRPF8pre-mRNA processing factor 8 | Often (30–79%) | In 1 condition |
| COL4A3collagen type IV alpha 3 chain | Sometimes (5–29%) | In 1 condition |
| COL4A4collagen type IV alpha 4 chain | Sometimes (5–29%) | In 1 condition |
| ABHD12abhydrolase domain containing 12, lysophospholipase | Not recorded | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Not recorded | In 1 condition |
| FZD4frizzled class receptor 4 | Not recorded | In 1 condition |
| LRP5LDL receptor related protein 5 | Not recorded | In 2 conditions |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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