Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

SPRTN

SprT-like N-terminal domain

Summary

Cytogenetic location
1q42.2
Coordinates
Chromosome 1: 231,338,293–231,355,023 (GRCh38)
Exons
5 exons across 16.7 kb
Protein
489 amino acids
Also known as
DKFZP547N043, Spartan, DVC1
Previous symbols
C1orf124
MANE Select transcript
ENST00000295050.12NM_032018.7
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads SPRTN yet. The test sequences your whole genome, so your data includes it all the same.

How SPRTN is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 1, with a bracket where SPRTN sits. SPRTN and 13 genes near it on chromosome 1, from 230,846,658 to 231,846,657.Chromosome 11q42.2p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44231 Mb231.2 Mb231.4 Mb231.6 Mb231.8 MbC1orf198: 230,837,119–230,869,589, reverse strandC1orf198TTC13: 230,902,936–230,978,893, reverse strandTTC13ARV1: 230,978,981–231,000,735, forward strandARV1FAM89A: 230,999,826–231,040,270, reverse strandFAM89ATRIM67: 231,162,058–231,221,565, forward strandTRIM67FSAF1: 231,223,763–231,241,187, reverse strandFSAF1GNPAT: 231,241,184–231,277,973, forward strandGNPATEXOC8: 231,332,753–231,337,852, reverse strandEXOC8SPRTN: 231,338,293–231,355,023, forward strandSPRTNEGLN1: 231,359,560–231,422,749, reverse strandEGLN1: 231,363,797–231,528,603, reverse strandTSNAX: 231,528,541–231,566,524, forward strandTSNAXTSNAX-DISC1: 231,528,653–231,819,244, forward strandTSNAX-DISC1DISC1: 231,626,663–232,041,272, forward strandDISC1Diagram of SPRTN: 5 exons on the forward strand of chromosome 1Exon 5: 1 known disease-causing siteExon 1: 231,338,293–231,338,604, 312 basesExon 2: 231,339,769–231,339,868, 100 basesExon 3: 231,347,797–231,347,925, 129 basesExon 4: 231,351,304–231,351,571, 268 basesExon 5: 231,352,610–231,355,023, 2,414 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.2 kb of the gene's 16.7 kb; 1,470 of those bases code for the protein.

Sequencing SPRTN

1

position in SPRTN where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 16.7 kb of SPRTN, introns included, not only the 3.2 kb of exons.

Traits linked to SPRTN

The Human Phenotype Ontology lists these as features of the rare conditions SPRTN can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SPRTN gene: SprT-like N-terminal domain. Retrieved 17 October 2026, from https://dantelabs.com/genes/sprtn

Vancouver

Dante Labs. SPRTN gene: SprT-like N-terminal domain [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sprtn

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test