Trait
Gum disease
Clinical name: Periodontitis
Inflammation of the periodontium.
Summary
- Also called
- Pyorrhea
Reference genomeGRCh38hg38
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Get my Genome Test38 genes linked to Gum disease
Changes in these genes cause rare conditions in which Gum disease is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AEBP1AE binding protein 1 | Always | In 2 conditions |
| AP3B1adaptor related protein complex 3 subunit beta 1 | Always | In 1 condition |
| C1Rcomplement C1r | Very often (80–99%) | In 1 condition |
| C1Scomplement C1s | Very often (80–99%) | In 1 condition |
| CTSCcathepsin C | Very often (80–99%) | In 2 conditions |
| NOTCH2notch receptor 2 | Very often (80–99%) | In 1 condition |
| ACDACD shelterin complex subunit and telomerase recruitment factor | Often (30–79%) | In 1 condition |
| CLPBClpB family mitochondrial disaggregase | Often (30–79%) | In 1 condition |
| CTC1CST telomere replication complex component 1 | Often (30–79%) | In 1 condition |
| DKC1dyskerin pseudouridine synthase 1 | Often (30–79%) | In 1 condition |
| ELANEelastase, neutrophil expressed | Often (30–79%) | In 2 conditions |
| FERMT1FERM domain containing kindlin 1 | Often (30–79%) | In 2 conditions |
| FGF3fibroblast growth factor 3 | Often (30–79%) | In 1 condition |
| GFI1growth factor independent 1 transcriptional repressor | Often (30–79%) | In 1 condition |
| LYSTlysosomal trafficking regulator | Often (30–79%) | In 2 conditions |
| MIA3MIA SH3 domain ER export factor 3 | Often (30–79%) | In 1 condition |
| NHP2NHP2 ribonucleoprotein | Often (30–79%) | In 1 condition |
| NOP10NOP10 ribonucleoprotein | Often (30–79%) | In 1 condition |
| NPM1nucleophosmin 1 | Often (30–79%) | In 1 condition |
| PARNpoly(A)-specific ribonuclease | Often (30–79%) | In 1 condition |
| RTEL1regulator of telomere elongation helicase 1 | Often (30–79%) | In 1 condition |
| SRP19signal recognition particle 19 | Often (30–79%) | In 1 condition |
| TCIRG1T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 | Often (30–79%) | In 1 condition |
| TERCtelomerase RNA component | Often (30–79%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 1 condition |
| TINF2TERF1 interacting nuclear factor 2 | Often (30–79%) | In 1 condition |
| TYMSthymidylate synthetase | Often (30–79%) | In 1 condition |
| USB1U6 snRNA biogenesis phosphodiesterase 1 | Often (30–79%) | In 1 condition |
| WRAP53WD repeat containing antisense to TP53 | Often (30–79%) | In 1 condition |
| COL3A1collagen type III alpha 1 chain | Sometimes (5–29%) | In 2 conditions |
| FAM20AFAM20A golgi associated secretory pathway pseudokinase | Sometimes (5–29%) | In 1 condition |
| LEF1lymphoid enhancer binding factor 1 | Sometimes (5–29%) | In 1 condition |
| OCRLOCRL inositol polyphosphate-5-phosphatase | Sometimes (5–29%) | In 1 condition |
| PLGplasminogen | Sometimes (5–29%) | In 2 conditions |
| SLC37A4solute carrier family 37 member 4 | Sometimes (5–29%) | In 1 condition |
| GORABgolgin, RAB6 interacting | Not recorded | In 1 condition |
| ITGB2integrin subunit beta 2 | Not recorded | In 1 condition |
| SLC35C1solute carrier family 35 member C1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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