Trait
Exercise-induced muscle pain
Clinical name: Exercise-induced myalgia
The occurrence of an unusually high amount of muscle pain following exercise.
Summary
- Also called
- Muscle pain on exercise, Muscle pain with exercise, Muscle pain, exercise-induced
- Body system
- Constitutional symptom
Reference genomeGRCh38hg38
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Get my Genome Test39 genes linked to Exercise-induced muscle pain
Changes in these genes cause rare conditions in which Exercise-induced muscle pain is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FILIP1filamin A interacting protein 1 | Always | In 1 condition |
| GYS1glycogen synthase 1 | Always | In 1 condition |
| HMGCR3-hydroxy-3-methylglutaryl-CoA reductase | Always | In 1 condition |
| LMNAlamin A/C | Always | In 2 conditions |
| SLC25A42solute carrier family 25 member 42 | Always | In 1 condition |
| TMEM126Btransmembrane protein 126B | Always | In 1 condition |
| AMPD1adenosine monophosphate deaminase 1 | Very often (80–99%) | In 2 conditions |
| AMPD3adenosine monophosphate deaminase 3 | Very often (80–99%) | In 1 condition |
| CPT2carnitine palmitoyltransferase 2 | Very often (80–99%) | In 2 conditions |
| FLNCfilamin C | Very often (80–99%) | In 1 condition |
| ACADMacyl-CoA dehydrogenase medium chain | Often (30–79%) | In 1 condition |
| ANO5anoctamin 5 | Often (30–79%) | In 1 condition |
| DYSFdysferlin | Often (30–79%) | In 2 conditions |
| HNRNPA1heterogeneous nuclear ribonucleoprotein A1 | Often (30–79%) | In 1 condition |
| LDHAlactate dehydrogenase A | Often (30–79%) | In 1 condition |
| LPIN1lipin 1 | Often (30–79%) | In 1 condition |
| MATR3matrin 3 | Often (30–79%) | In 1 condition |
| MLIPmuscular LMNA interacting protein | Often (30–79%) | In 1 condition |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Often (30–79%) | In 1 condition |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Often (30–79%) | In 1 condition |
| OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | Often (30–79%) | In 1 condition |
| PFKMphosphofructokinase, muscle | Often (30–79%) | In 1 condition |
| PGK1phosphoglycerate kinase 1 | Often (30–79%) | In 1 condition |
| RNASEH1ribonuclease H1 | Often (30–79%) | In 1 condition |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Often (30–79%) | In 1 condition |
| BIN1bridging integrator 1 | Sometimes (5–29%) | In 1 condition |
| DNM2dynamin 2 | Sometimes (5–29%) | In 1 condition |
| MTMR14myotubularin related protein 14 | Sometimes (5–29%) | In 1 condition |
| MYF6myogenic factor 6 | Sometimes (5–29%) | In 1 condition |
| PMP22peripheral myelin protein 22 | Sometimes (5–29%) | In 1 condition |
| PYGMglycogen phosphorylase, muscle associated | Sometimes (5–29%) | In 2 conditions |
| RYR1ryanodine receptor 1 | Sometimes (5–29%) | In 3 conditions |
| TPM2tropomyosin 2 | Sometimes (5–29%) | In 1 condition |
| ACADVLacyl-CoA dehydrogenase very long chain | Not recorded | In 1 condition |
| CAV3caveolin 3 | Not recorded | In 1 condition |
| PGAM2phosphoglycerate mutase 2 | Not recorded | In 1 condition |
| PHKA1phosphorylase kinase regulatory subunit alpha 1 | Not recorded | In 1 condition |
| STIM1stromal interaction molecule 1 | Not recorded | In 1 condition |
| TRIM32tripartite motif containing 32 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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