Trait
Right and left cleft palate
Clinical name: Bilateral cleft palate
Nonmidline cleft palate on the left and right sides.
Summary
- Also called
- Bilateral palatoschisis
- Body system
- Abnormality of head or neck
Reference genomeGRCh38hg38
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Get my Genome Test28 genes linked to Right and left cleft palate
Changes in these genes cause rare conditions in which Right and left cleft palate is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AMOTL1angiomotin like 1 | Always | In 1 condition |
| CHUKcomponent of inhibitor of nuclear factor kappa B kinase complex | Always | In 1 condition |
| DLX4distal-less homeobox 4 | Always | In 2 conditions |
| DMRT2doublesex and mab-3 related transcription factor 2 | Always | In 1 condition |
| KCNK3potassium two pore domain channel subfamily K member 3 | Always | In 1 condition |
| MED16mediator complex subunit 16 | Always | In 1 condition |
| RPL26ribosomal protein L26 | Always | In 1 condition |
| HYAL2hyaluronidase 2 | Very often (80–99%) | In 1 condition |
| MED12mediator complex subunit 12 | Often (30–79%) | In 1 condition |
| SIX3SIX homeobox 3 | Often (30–79%) | In 1 condition |
| ARHGAP29Rho GTPase activating protein 29 | Sometimes (5–29%) | In 1 condition |
| ARHGEF38Rho guanine nucleotide exchange factor 38 | Sometimes (5–29%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Sometimes (5–29%) | In 1 condition |
| BMP4bone morphogenetic protein 4 | Sometimes (5–29%) | In 1 condition |
| CDH1cadherin 1 | Sometimes (5–29%) | In 1 condition |
| COBLL1cordon-bleu WH2 repeat protein like 1 | Sometimes (5–29%) | In 1 condition |
| DLG1discs large MAGUK scaffold protein 1 | Sometimes (5–29%) | In 1 condition |
| GLI2GLI family zinc finger 2 | Sometimes (5–29%) | In 1 condition |
| IRF6interferon regulatory factor 6 | Sometimes (5–29%) | In 1 condition |
| MAU2MAU2 sister chromatid cohesion factor | Sometimes (5–29%) | In 1 condition |
| MSX1msh homeobox 1 | Sometimes (5–29%) | In 1 condition |
| NECTIN1nectin cell adhesion molecule 1 | Sometimes (5–29%) | In 1 condition |
| PDGFRAplatelet derived growth factor receptor alpha | Sometimes (5–29%) | In 1 condition |
| PTCH1patched 1 | Sometimes (5–29%) | In 1 condition |
| RIC1RIC1 partner of RAB6A GEF complex | Sometimes (5–29%) | In 1 condition |
| SLC26A2solute carrier family 26 member 2 | Sometimes (5–29%) | In 1 condition |
| SPOPspeckle type BTB/POZ protein | Sometimes (5–29%) | In 1 condition |
| TP63tumor protein p63 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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