Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

CHUK

component of inhibitor of nuclear factor kappa B kinase complex

Summary

Cytogenetic location
10q24.31
Coordinates
Chromosome 10: 100,188,300–100,229,596 (GRCh38)
Exons
21 exons across 41.3 kb
Protein
745 amino acids
Also known as
IKK1, IKK-alpha, IkBKA, NFKBIKA, IKKA
Previous symbols
TCF16
MANE Select transcript
ENST00000370397.8NM_001278.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads CHUK yet. The test sequences your whole genome, so your data includes it all the same.

How CHUK is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 10, with a bracket where CHUK sits. CHUK and 17 genes near it on chromosome 10, from 99,708,948 to 100,708,947.Chromosome 1010q24.31p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.399.8 Mb100 Mb100.2 Mb100.4 Mb100.6 Mb: 99,651,595–99,732,112, reverse strandENTPD7: 99,659,415–99,712,489, forward strandENTPD7COX15: 99,694,554–99,732,858, reverse strandCOX15CUTC: 99,702,558–99,758,005, forward strandCUTCABCC2: 99,782,640–99,853,670, forward strandABCC2DNMBP: 99,875,576–100,010,049, reverse strandDNMBPCPN1: 100,041,105–100,081,907, reverse strandCPN1ERLIN1: 100,150,094–100,186,062, reverse strandERLIN1CHUK: 100,188,300–100,229,596, reverse strandCHUKCWF19L1: 100,230,024–100,267,685, reverse strandCWF19L1BLOC1S2: 100,272,797–100,286,708, reverse strandBLOC1S2PKD2L1: 100,288,149–100,330,264, reverse strandPKD2L1SCD: 100,346,508–100,364,837, forward strandSCDWNT8B: 100,463,009–100,483,744, forward strandWNT8BSEC31B: 100,484,998–100,519,892, reverse strandSEC31B: 100,505,628–100,529,881, reverse strandNDUFB8: 100,523,668–100,530,000, reverse strandNDUFB8HIF1AN: 100,529,072–100,681,896, forward strandHIF1ANDiagram of CHUK: 21 exons on the reverse strand of chromosome 10Exon 21: 100,188,300–100,189,627, 1,328 basesExon 20: 100,190,869–100,190,968, 100 basesExon 19: 100,193,298–100,193,431, 134 basesExon 18: 100,193,984–100,194,131, 148 basesExon 17: 100,194,425–100,194,521, 97 basesExon 16: 100,199,971–100,200,020, 50 basesExon 15: 100,200,671–100,200,780, 110 basesExon 14: 100,202,088–100,202,149, 62 basesExon 13: 100,204,506–100,204,657, 152 basesExon 12: 100,205,076–100,205,199, 124 basesExon 11: 100,207,230–100,207,332, 103 basesExon 10: 100,209,595–100,209,789, 195 basesExon 9: 100,217,995–100,218,130, 136 basesExon 8: 100,218,718–100,218,825, 108 basesExon 7: 100,219,008–100,219,132, 125 basesExon 6: 100,219,270–100,219,359, 90 basesExon 5: 100,220,588–100,220,676, 89 basesExon 4: 100,222,112–100,222,181, 70 basesExon 3: 100,222,866–100,222,980, 115 basesExon 2: 100,225,923–100,226,017, 95 basesExon 1: 100,229,428–100,229,596, 169 bases21201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.6 kb of the gene's 41.3 kb; 2,238 of those bases code for the protein.

Traits linked to CHUK

The Human Phenotype Ontology lists these as features of the rare conditions CHUK can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). CHUK gene: component of inhibitor of nuclear factor kappa B kinase complex. Retrieved 17 October 2026, from https://dantelabs.com/genes/chuk

Vancouver

Dante Labs. CHUK gene: component of inhibitor of nuclear factor kappa B kinase complex [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/chuk

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test