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Gene

CACNB2

calcium voltage-gated channel auxiliary subunit beta 2

Summary

Cytogenetic location
10p12
Coordinates
Chromosome 10: 18,140,424–18,543,557 (GRCh38)
Exons
14 exons across 403.1 kb
Protein
660 amino acids
Previous symbols
MYSB, CACNLB2
MANE Select transcript
ENST00000324631.13NM_201596.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CACNB2 yet. The test sequences your whole genome, so your data includes it all the same.

How CACNB2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 10, with a bracket where CACNB2 sits. CACNB2 and 5 genes near it on chromosome 10, from 17,737,290 to 18,946,691.Chromosome 1010p12p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.317.8 Mb18 Mb18.2 Mb18.4 Mb18.6 Mb18.8 MbTMEM236: 17,752,201–17,800,868, forward strandTMEM236MRC1: 17,809,014–17,911,607, forward strandMRC1SLC39A12: 17,951,825–18,043,292, forward strandSLC39A12CACNB2: 18,140,424–18,543,557, forward strandCACNB2NSUN6: 18,542,901–18,659,285, reverse strandNSUN6ARL5B: 18,659,304–18,681,640, forward strandARL5BDiagram of CACNB2: 14 exons on the forward strand of chromosome 10Exon 14: 1 known disease-causing siteExon 1: 18,140,424–18,140,856, 433 basesExon 2: 18,150,883–18,150,975, 93 basesExon 3: 18,401,924–18,402,043, 120 basesExon 4: 18,498,355–18,498,477, 123 basesExon 5: 18,500,812–18,500,948, 137 basesExon 6: 18,506,471–18,506,547, 77 basesExon 7: 18,514,236–18,514,369, 134 basesExon 8: 18,518,336–18,518,416, 81 basesExon 9: 18,518,910–18,518,968, 59 basesExon 10: 18,527,588–18,527,697, 110 basesExon 11: 18,534,076–18,534,227, 152 basesExon 12: 18,536,101–18,536,196, 96 basesExon 13: 18,538,180–18,538,365, 186 basesExon 14: 18,539,230–18,543,557, 4,328 bases1510145′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.1 kb of the gene's 403.1 kb; 1,983 of those bases code for the protein.

How a genome test reads CACNB2

1

position in CACNB2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 403.1 kb of CACNB2, introns included, not only the 6.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CACNB2 gene: calcium voltage-gated channel auxiliary subunit beta 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/cacnb2

Vancouver

Dante Labs. CACNB2 gene: calcium voltage-gated channel auxiliary subunit beta 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/cacnb2

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