Trait
Accessory nipple
Clinical name: Supernumerary nipple
Presence of more than two nipples.
Summary
- Also called
- Accessory nipples, accessory mamilla, Increased nipple number
- Body system
- Abnormality of the breast
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test57 genes linked to Accessory nipple
Changes in these genes cause rare conditions in which Accessory nipple is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ARHGAP31Rho GTPase activating protein 31 | Always | In 1 condition |
| DMRT2doublesex and mab-3 related transcription factor 2 | Always | In 1 condition |
| TP63tumor protein p63 | Always | In 2 conditions |
| UBA2ubiquitin like modifier activating enzyme 2 | Always | In 1 condition |
| WDR19WD repeat domain 19 | Always | In 1 condition |
| ACTBactin beta | Very often (80–99%) | In 1 condition |
| DHODHdihydroorotate dehydrogenase (quinone) | Very often (80–99%) | In 2 conditions |
| GPC3glypican 3 | Very often (80–99%) | In 2 conditions |
| GPC4glypican 4 | Very often (80–99%) | In 1 condition |
| CHAMP1chromosome alignment maintaining phosphoprotein 1 | Often (30–79%) | In 1 condition |
| COLEC10collectin subfamily member 10 | Often (30–79%) | In 1 condition |
| COLEC11collectin subfamily member 11 | Often (30–79%) | In 1 condition |
| H4C9H4 clustered histone 9 | Often (30–79%) | In 1 condition |
| HDAC4histone deacetylase 4 | Often (30–79%) | In 1 condition |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Often (30–79%) | In 3 conditions |
| KDM5Blysine demethylase 5B | Often (30–79%) | In 1 condition |
| MASP1MBL associated serine protease 1 | Often (30–79%) | In 2 conditions |
| MDH2malate dehydrogenase 2 | Often (30–79%) | In 1 condition |
| TSHZ3teashirt zinc finger homeobox 3 | Often (30–79%) | In 1 condition |
| ASXL3ASXL transcriptional regulator 3 | Sometimes (5–29%) | In 1 condition |
| BCL11ABCL11 transcription factor A | Sometimes (5–29%) | In 1 condition |
| CDH2cadherin 2 | Sometimes (5–29%) | In 1 condition |
| CKAP2Lcytoskeleton associated protein 2L | Sometimes (5–29%) | In 1 condition |
| CSPP1centrosome and spindle pole associated protein 1 | Sometimes (5–29%) | In 1 condition |
| DDX6DEAD-box helicase 6 | Sometimes (5–29%) | In 1 condition |
| GDF11growth differentiation factor 11 | Sometimes (5–29%) | In 1 condition |
| HS2ST1heparan sulfate 2-O-sulfotransferase 1 | Sometimes (5–29%) | In 1 condition |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Sometimes (5–29%) | In 2 conditions |
| JARID2jumonji and AT-rich interaction domain containing 2 | Sometimes (5–29%) | In 1 condition |
| KDM1Alysine demethylase 1A | Sometimes (5–29%) | In 2 conditions |
| KIAA0586KIAA0586 | Sometimes (5–29%) | In 1 condition |
| NONOnon-POU domain containing octamer binding | Sometimes (5–29%) | In 1 condition |
| PGAP2post-GPI attachment to proteins 2 | Sometimes (5–29%) | In 1 condition |
| PGAP3post-GPI attachment to proteins phospholipase 3 | Sometimes (5–29%) | In 1 condition |
| PIGLphosphatidylinositol glycan anchor biosynthesis class L | Sometimes (5–29%) | In 1 condition |
| PIGOphosphatidylinositol glycan anchor biosynthesis class O | Sometimes (5–29%) | In 1 condition |
| PIGVphosphatidylinositol glycan anchor biosynthesis class V | Sometimes (5–29%) | In 1 condition |
| PIGWphosphatidylinositol glycan anchor biosynthesis class W | Sometimes (5–29%) | In 1 condition |
| PIGYphosphatidylinositol glycan anchor biosynthesis class Y | Sometimes (5–29%) | In 1 condition |
| PNPLA6patatin like domain 6, lysophospholipase | Sometimes (5–29%) | In 1 condition |
Show 17 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| RELREL proto-oncogene, NF-kB subunit | Sometimes (5–29%) | In 1 condition |
| RNF216ring finger protein 216 | Sometimes (5–29%) | In 1 condition |
| STAG1STAG1 cohesin complex component | Sometimes (5–29%) | In 1 condition |
| TCF4transcription factor 4 | Sometimes (5–29%) | In 2 conditions |
| TFAP2Btranscription factor AP-2 beta | Sometimes (5–29%) | In 1 condition |
| TNRC6Btrinucleotide repeat containing adaptor 6B | Sometimes (5–29%) | In 1 condition |
| TRRAPtransformation/transcription domain associated protein | Sometimes (5–29%) | In 1 condition |
| XPO1exportin 1 | Sometimes (5–29%) | In 1 condition |
| ZMYND11zinc finger MYND-type containing 11 | Sometimes (5–29%) | In 1 condition |
| PORCNporcupine O-acyltransferase | Rarely (1–4%) | In 2 conditions |
| PPP2R5Dprotein phosphatase 2 regulatory subunit B'delta | Rarely (1–4%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Not recorded | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Not recorded | In 1 condition |
| MEGF8multiple EGF like domains 8 | Not recorded | In 1 condition |
| TFAP2Atranscription factor AP-2 alpha | Not recorded | In 1 condition |
| TMCO1transmembrane and coiled-coil domains 1 | Not recorded | In 1 condition |
| ZEB2zinc finger E-box binding homeobox 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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