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Gene

SMURF1

SMAD specific E3 ubiquitin protein ligase 1

Summary

Cytogenetic location
7q22.1
Coordinates
Chromosome 7: 99,027,440–99,144,108 (GRCh38)
Exons
18 exons across 116.7 kb
Protein
731 amino acids
Also known as
KIAA1625
MANE Select transcript
ENST00000361368.7NM_181349.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SMURF1 yet. The test sequences your whole genome, so your data includes it all the same.

How SMURF1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 7, with a bracket where SMURF1 sits. SMURF1 and 20 genes near it on chromosome 7, from 98,585,774 to 99,585,773.Chromosome 77q22.1p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.398.6 Mb98.8 Mb99 Mb99.2 Mb99.4 MbNPTX2: 98,617,254–98,629,870, forward strandNPTX2TMEM130: 98,846,478–98,870,771, reverse strandTMEM130TRRAP: 98,877,933–99,050,831, forward strandTRRAPSMURF1: 99,027,440–99,144,108, reverse strandSMURF1KPNA7: 99,173,572–99,250,075, reverse strandKPNA7MYH16: 99,272,839–99,311,132, forward strandMYH16ARPC1A: 99,325,879–99,366,527, forward strandARPC1A: 99,325,879–99,394,653, forward strandARPC1B: 99,374,226–99,398,124, forward strandARPC1BPDAP1: 99,392,048–99,408,831, reverse strandPDAP1BUD31: 99,408,610–99,419,618, forward strandBUD31PTCD1: 99,415,192–99,466,201, reverse strandPTCD1ATP5MF-PTCD1: 99,419,749–99,466,197, reverse strandCPSF4: 99,438,908–99,458,910, forward strandATP5MF: 99,448,475–99,466,201, reverse strandATP5MFZNF789: 99,472,794–99,503,650, forward strandZNF394: 99,473,877–99,504,918, reverse strandZKSCAN5: 99,504,634–99,535,360, forward strandZKSCAN5ZBED8L: 99,546,204–99,559,392, reverse strandZBED8LZNF655: 99,558,389–99,578,948, forward strandZNF655: 99,558,695–99,607,810, forward strandDiagram of SMURF1: 18 exons on the reverse strand of chromosome 7Exon 18: 99,027,440–99,030,683, 3,244 basesExon 17: 99,033,037–99,033,121, 85 basesExon 16: 99,035,515–99,035,716, 202 basesExon 15: 99,037,067–99,037,187, 121 basesExon 14: 99,038,388–99,038,525, 138 basesExon 13: 99,040,378–99,040,556, 179 basesExon 12: 99,042,118–99,042,232, 115 basesExon 11: 99,045,698–99,045,801, 104 basesExon 10: 99,047,684–99,047,882, 199 basesExon 9: 99,049,563–99,049,709, 147 basesExon 8: 99,051,357–99,051,441, 85 basesExon 7: 99,052,205–99,052,446, 242 basesExon 6: 99,054,790–99,054,865, 76 basesExon 5: 99,057,205–99,057,270, 66 basesExon 4: 99,057,418–99,057,551, 134 basesExon 3: 99,060,599–99,060,707, 109 basesExon 2: 99,061,799–99,061,837, 39 basesExon 1: 99,143,726–99,144,108, 383 bases1816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.7 kb of the gene's 116.7 kb; 2,196 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SMURF1 gene: SMAD specific E3 ubiquitin protein ligase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/smurf1

Vancouver

Dante Labs. SMURF1 gene: SMAD specific E3 ubiquitin protein ligase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/smurf1

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