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Gene

NXN

nucleoredoxin

Summary

Cytogenetic location
17p13.3
Coordinates
Chromosome 17: 799,310–979,776 (GRCh38)
Exons
8 exons across 180.5 kb
Protein
435 amino acids
Also known as
FLJ12614, NRX
MANE Select transcript
ENST00000336868.8NM_022463.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NXN yet. The test sequences your whole genome, so your data includes it all the same.

How NXN is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 17, with a bracket where NXN sits. NXN and 12 genes near it on chromosome 17, from 389,543 to 1,389,542.Chromosome 1717p13.3p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.30.4 Mb0.6 Mb0.8 Mb1 Mb1.2 MbLIAT1: 410,302–431,062, forward strandLIAT1RFLNB: 439,978–445,939, reverse strandRFLNBVPS53: 508,503–721,717, reverse strandVPS53TLCD3A: 732,412–743,009, forward strandTLCD3AGEMIN4: 742,840–753,999, reverse strandGEMIN4GLOD4: 757,097–782,341, reverse strandGLOD4MRM3: 782,342–792,510, forward strandMRM3NXN: 799,310–979,776, reverse strandNXNTIMM22: 997,090–1,003,671, forward strandTIMM22ABR: 1,003,519–1,229,738, reverse strandABRBHLHA9: 1,270,444–1,271,815, forward strandBHLHA9TRARG1: 1,279,554–1,300,978, forward strandTRARG1YWHAE: 1,344,275–1,400,326, reverse strandYWHAEDiagram of NXN: 8 exons on the reverse strand of chromosome 17Exon 5: 1 known disease-causing siteExon 8: 799,310–801,131, 1,822 basesExon 7: 803,682–803,806, 125 basesExon 6: 805,068–805,247, 180 basesExon 5: 819,439–819,545, 107 basesExon 4: 822,357–822,457, 101 basesExon 3: 823,632–823,765, 134 basesExon 2: 825,961–826,078, 118 basesExon 1: 979,319–979,776, 458 bases864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3 kb of the gene's 180.5 kb; 1,308 of those bases code for the protein.

How a genome test reads NXN

1

position in NXN where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 180.5 kb of NXN, introns included, not only the 3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NXN gene: nucleoredoxin. Retrieved 17 October 2026, from https://dantelabs.com/genes/nxn

Vancouver

Dante Labs. NXN gene: nucleoredoxin [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/nxn

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