Skip to content
Use your HSA or FSA funds

Gene

MT-TI

mitochondrially encoded tRNA-Ile (AUU/C)

Summary

Cytogenetic location
mitochondria
Inheritance
Autosomal dominant
Also known as
trnI
Previous symbols
MTTI
Locus type
RNA, transfer

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    • Hypertrophic Cardiomyopathy

      • Autosomal dominant

        One of 62 genes linked to it

        A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract.

        • ClinGen rates the link moderate
        What knowing changes

        Beta-blockers, non-dihydropyridine calcium channel blockers, activity restriction, genetic counseling

    Inheritance

    Autosomal dominant
    One changed copy, from either parent, is enough. A parent who has one passes it on to each child with a one-in-two chance.

    How a genome test reads MT-TI

    1

    position in MT-TI where ClinVar classes a change as pathogenic or likely pathogenic

    None of them falls in a region short reads find hard.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). MT-TI gene: mitochondrially encoded tRNA-Ile (AUU/C). Retrieved 17 October 2026, from https://dantelabs.com/genes/mt-ti

    Vancouver

    Dante Labs. MT-TI gene: mitochondrially encoded tRNA-Ile (AUU/C) [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mt-ti

    One test. A lifetime of answers.

    From $449Free shipping · Results in 6–8 weeks

    Get my Genome Test