Gene
JRK
Jrk helix-turn-helix protein
- HGNC 6199↗(opens in a new tab)
- Ensembl gene ENSG00000234616↗(opens in a new tab)
- NCBI Gene 8629↗(opens in a new tab)
Summary
- Cytogenetic location
- 8q24.3
- Coordinates
- Chromosome 8: 142,657,460–142,669,967 (GRCh38)
- Exons
- 2 exons across 12.5 kb
- Protein
- 568 amino acids
- Also known as
- JH8, jerky
- MANE Select transcript
- ENST00000612905.2NM_003724.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How JRK is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 9.1 kb of the gene's 12.5 kb; 1,707 of those bases code for the protein.
Traits linked to JRK
The Human Phenotype Ontology lists these as features of the rare conditions JRK can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- EEG with polyspike wave complexes
- EEG with spike-wave complexes (2.5-3.5 Hz)
- Generalized-onset seizure
- Morning myoclonic jerks
- Typical absence seizure
- Attention deficit
- Abnormal social behavior
- Anxiety
Show 16 more traits
- Brief seizures with staring spells
- Depression
- Febrile seizure (within the age range of 3 months to 6 years)
- Grand mal seizures
- Impaired visuospatial constructive cognition
- Intellectual disability
- Low self-esteem
- Myoclonic absence seizure
- Photosensitive tonic-clonic seizure
- Punding
- Reading disability
- Specific learning disability
- Aggressive behavior
- Head jerking
- Limb myoclonus
- Repeated seizures without recovery between them
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). JRK gene: Jrk helix-turn-helix protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/jrk
Dante Labs. JRK gene: Jrk helix-turn-helix protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/jrk
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