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Trait
Underdeveloped inner lips
Clinical name: Hypoplastic labia minora
Summary
- Body system
- Abnormality of the genitourinary system
Underdeveloped inner lipsHP:0000064
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Read the genes linked to Underdeveloped inner lips, and the rest of your genome, with one test.
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Get my Genome Test35 genes linked to Underdeveloped inner lips
Changes in these genes cause rare conditions in which Underdeveloped inner lips is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| RBSNrabenosyn, RAB effector | Always | In 1 condition |
| TOP2BDNA topoisomerase II beta | Always | In 1 condition |
| CDC45cell division cycle 45 | Often (30–79%) | In 1 condition |
| CDC6cell division cycle 6 | Often (30–79%) | In 1 condition |
| CDT1chromatin licensing and DNA replication factor 1 | Often (30–79%) | In 1 condition |
| DVL1dishevelled segment polarity protein 1 | Often (30–79%) | In 1 condition |
| DVL3dishevelled segment polarity protein 3 | Often (30–79%) | In 1 condition |
| FZD2frizzled class receptor 2 | Often (30–79%) | In 1 condition |
| GMNNgeminin DNA replication inhibitor | Often (30–79%) | In 1 condition |
| HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Often (30–79%) | In 1 condition |
| MAGEL2MAGE family member L2 | Often (30–79%) | In 5 conditions |
| MKRN3makorin ring finger protein 3 | Often (30–79%) | In 1 condition |
| NDNnecdin, MAGE family member | Often (30–79%) | In 3 conditions |
| NPAP1nuclear pore associated protein 1 | Often (30–79%) | In 1 condition |
| OCA2OCA2 melanosomal transmembrane protein | Often (30–79%) | In 3 conditions |
| ORC1origin recognition complex subunit 1 | Often (30–79%) | In 2 conditions |
| ORC4origin recognition complex subunit 4 | Often (30–79%) | In 1 condition |
| ORC6origin recognition complex subunit 6 | Often (30–79%) | In 2 conditions |
| PWAR1Prader Willi/Angelman region RNA 1 | Often (30–79%) | In 1 condition |
| PWRN1Prader-Willi region non-protein coding RNA 1 | Often (30–79%) | In 1 condition |
| RAB18RAB18, member RAS oncogene family | Often (30–79%) | In 2 conditions |
| RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1 | Often (30–79%) | In 1 condition |
| RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2 | Often (30–79%) | In 1 condition |
| ROR2ROR family WNT receptor 2 | Often (30–79%) | In 1 condition |
| SIM1SIM bHLH transcription factor 1 | Often (30–79%) | In 1 condition |
| SNORD115-1small nucleolar RNA, C/D box 115-1 | Often (30–79%) | In 1 condition |
| SNORD116-1small nucleolar RNA, C/D box 116-1 | Often (30–79%) | In 1 condition |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Often (30–79%) | In 3 conditions |
| TBC1D20TBC1 domain family member 20 | Often (30–79%) | In 1 condition |
| WNT5AWnt family member 5A | Often (30–79%) | In 1 condition |
| ACTBactin beta | Sometimes (5–29%) | In 1 condition |
| GAD1glutamate decarboxylase 1 | Sometimes (5–29%) | In 1 condition |
| MAB21L1mab-21 like 1 | Sometimes (5–29%) | In 1 condition |
| TWIST2twist family bHLH transcription factor 2 | Sometimes (5–29%) | In 1 condition |
| SETBP1SET binding protein 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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